Evidence map›Paper›PMID 32705926›Full record

ArticleThe Journal of international medical research2020

Association between lipid profiles and arterial stiffness: A secondary analysis based on a cross-sectional study.

Long Wang, Fu Zhi, Beibei Gao, Jie Ni, Yihai Liu, Xuming Mo, Jinyu Huang

Abstract read
In one paragraph

Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  4. Pulse Wave Velocity Progression Determinants: No Significant Association with Novel Lipids Parameter.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
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  5. Article
  6. Review
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  8. Risk prediction score and equation for progression of arterial stiffness using Japanese longitudinal health examination data.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. The Impact of the Blood Lipids Levels on Arterial Stiffness.Journal of cardiovascular development and disease · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Long WangDepartment of Cardiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Fu ZhiDepartment of Cardiothoracic Surgery, Children's Hospital of Nanjing Medical University, 72 Guangzhou Road, Nanjing, China.
Beibei GaoDepartment of Cardiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Jie NiDepartment of Cardiology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University. Zhongshan Road 321, Nanjing, China.
Yihai LiuDepartment of Cardiology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University. Zhongshan Road 321, Nanjing, China.
Xuming MoDepartment of Cardiothoracic Surgery, Children's Hospital of Nanjing Medical University, 72 Guangzhou Road, Nanjing, China.
Jinyu HuangDepartment of Cardiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe relationship between lipid levels and arterial stiffness remains controversial. Therefore, we aimed to determine the relationship between lipid profiles and brachial-ankle pulse wave velocity (baPWV) as an indicator of arterial stiffness.

methodsA total of 909 participants aged 24 to 84 years were stratified into four baPWV quartiles in our study. Serum lipids, baPWV, and other variables of the participants were measured. Univariable and multivariable linear regression analyses were used to examine the relationships between lipid parameters and baPWV.

resultsThe highest baPWV quartile group had higher aspartate transaminase, alanine aminotransferase, plasma glucose, total cholesterol, triglyceride (TG), and low-density lipoprotein cholesterol levels and maximum ankle-brachial index, and lower high-density lipoprotein cholesterol levels and estimated glomerular filtration rate. Univariate regression analysis showed that total cholesterol, TG, and low-density lipoprotein cholesterol levels were positively related and high-density lipoprotein cholesterol levels were negatively related to baPWV. After adjusting for age, body mass index, smoking status, aspartate transaminase, alanine aminotransferase, plasma glucose, and estimated glomerular filtration rate, only TG levels were correlated with baPWV (β = 0.075).

conclusionsFour lipid variates are associated with arterial stiffness, and TG levels are positively related to arterial stiffness, independent of cardiovascular risks and liver function.

Indexed as

Vascular StiffnessAdultAgedAged, 80 and overAnkle Brachial IndexCross-Sectional StudiesHumansLipidsMiddle AgedPulse Wave AnalysisRisk FactorsYoung AdultLipidsArterial stiffnessbrachial–ankle pulse-wave velocityestimated glomerular filtration ratelipid profileplasma glucosetriglycerides

Identifiers

PMID32705926
PMCPMC7383716

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.