Evidence map›Paper›PMID 32705911›Full record

ArticleJournal of feline medicine and surgery2021

Effect of a struvite dissolution diet in cats with naturally occurring struvite urolithiasis.

Karen M Tefft, Julie K Byron, Eric T Hostnik, Leighann Daristotle, Victoria Carmella, Nolan Z Frantz

Open access · hybridAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Karen M TefftDepartment of Clinical Sciences, North Carolina State University, Raleigh, NC, USA.ORCID 0000-0003-4523-9763
Julie K ByronDepartment of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH, USA.ORCID 0000-0001-9650-0197
Eric T HostnikDepartment of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH, USA.
Leighann DaristotleBlue Buffalo Company, Wilton, CT, USA.
Victoria CarmellaBlue Buffalo Company, Wilton, CT, USA.
Nolan Z FrantzBlue Buffalo Company, Wilton, CT, USA.
The Ohio State University · USNorth Carolina State University · US

Funding

The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve HealthUL1TR002733 · NCATS · OHIO STATE UNIVERSITY · PI RINGEL, MATTHEW D · 2018 to 2022
$28.9M
NCATS NIH HHS UL1 TR002733
6 · The paper itself

Abstract

objectivesThe aim of the study was to determine the efficacy of the low struvite relative supersaturation diet in dissolution of feline struvite cystoliths.

methodsThis was a prospective, open-label, two-center study. Twelve client-owned cats were enrolled based on the radiographic appearance of their uroliths and urinalysis parameters. Cats were fed the test diet exclusively for up to 56 days. Cats were radiographed every other week until radiographic evidence of dissolution occurred or the end of the study period was reached. Cats with radiographically apparent uroliths at the end of the study period underwent cystotomy for stone retrieval and analysis.

resultsNine of the 12 cats completed the study. Eight experienced radiographic dissolution; seven of these had complete dissolution within the first month of treatment. One cat, whose owner declined cystotomy after partial dissolution at day 56, had complete radiographic resolution at 70 days of treatment. Two calcium oxalate urolith cores were removed from a cat that had partial radiographic dissolution. CONCLUSIONS AND RELEVANCE: The test diet was successful in dissolving suspected struvite cystoliths. As this diet is suitable for maintenance feeding of adult cats, it may be a suitable choice for long-term prevention of feline struvite urolithiasis.

Indexed as

Cat DiseasesUrinary Bladder CalculiUrolithiasisAnimalsCatsDietMagnesium CompoundsPhosphatesProspective StudiesSolubilityStruviteMagnesium CompoundsPhosphatesStruviteBladder stonescystolithmagnesium ammonium phosphatenutritional managementsterile struvite

Identifiers

PMID32705911
PMCPMC8008402
OpenAlexW3044057897

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.