Evidence map›Paper›PMID 32705815›Full record

ArticleESC heart failure2020

Sex differences in patients with acute decompensated heart failure in Japan: observation from the KCHF registry.

Erika Yamamoto, Takao Kato, Hidenori Yaku, Takeshi Morimoto, Yasutaka Inuzuka, Yodo Tamaki, Neiko Ozasa, Takeshi Kitai, Ryoji Taniguchi, Moritake Iguchi and 24 more

Abstract read
In one paragraph

Article in ESC heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Letter to the editor: Comments on gender differences in acute heart failure study.International journal of cardiology. Cardiovascular risk and prevention · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Prognostic Clinical Phenotypes of Patients with Acute Decompensated Heart Failure.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023
    Article
  11. Review
  12. Article
  13. Observational
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Erika YamamotoDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Kyoto, Japan.
Takao KatoDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Kyoto, Japan.
Hidenori YakuDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Kyoto, Japan.
Takeshi MorimotoDepartment of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
Yasutaka InuzukaDepartment of Cardiovascular Medicine, Shiga General Hospital, Moriyama, Shiga, Japan.
Yodo TamakiDivision of Cardiology, Tenri Hospital, Tenri, Nara, Japan.
Neiko OzasaDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Kyoto, Japan.
Takeshi KitaiDepartment of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan.
Ryoji TaniguchiDepartment of Cardiology, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Hyogo, Japan.
Moritake IguchiDepartment of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Kyoto, Japan.
Masashi KatoDepartment of Cardiology, Mitsubishi Kyoto Hospital, Kyoto, Kyoto, Japan.
Mamoru TakahashiDepartment of Cardiology, Shimabara Hospital, Kyoto, Kyoto, Japan.
Toshikazu JinnaiDepartment of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Shiga, Japan.
Tomoyuki IkedaDepartment of Cardiology, Hikone Municipal Hospital, Hikone, Shiga, Japan.
Yoshihiro HimuraDepartment of Cardiology, Hikone Municipal Hospital, Hikone, Shiga, Japan.
Kazuya NagaoDepartment of Cardiology, Osaka Red Cross Hospital, Osaka, Osaka, Japan.
Takafumi KawaiDepartment of Cardiology, Kishiwada City Hospital, Kishiwada, Osaka, Japan.
Akihiro KomasaDepartment of Cardiology, Kansai Electric Power Hospital, Osaka, Osaka, Japan.
Ryusuke NishikawaDepartment of Cardiology, Shizuoka General Hospital, Shizuoka, Shizuoka, Japan.
Yuichi KawaseDepartment of Cardiology, Kurashiki Central Hospital, Kurashiki, Okayama, Japan.
Takashi MorinagaDepartment of Cardiology, Kokura Memorial Hospital, Kokura, Fukuoka, Japan.
Mitsunori KawatoDepartment of Cardiology, Japanese Red Cross Wakayama Medical Center, Wakayama, Wakayama, Japan.
Yuta SekoDepartment of Cardiology, Kobe City Nishi-Kobe Medical Center, Kobe, Hyogo, Japan.
Mamoru ToyofukuKitano Hospital, Osaka, Osaka, Japan.
Yutaka FurukawaDepartment of Cardiology, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Hyogo, Japan.
Yoshihisa NakagawaDepartment of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan.
Kenji AndoDepartment of Cardiology, Kokura Memorial Hospital, Kokura, Fukuoka, Japan.
Kazushige KadotaDepartment of Cardiology, Kurashiki Central Hospital, Kurashiki, Okayama, Japan.
Satoshi ShizutaDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Kyoto, Japan.
Koh OnoDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Kyoto, Japan.
Yukihito SatoDepartment of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Kyoto, Japan.
Koichiro KuwaharaDepartment of Cardiovascular Medicine, Shinshu University Graduate School of Medicine, Matsumoto, Nagano, Japan.
Takeshi KimuraDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Kyoto, Japan.
KCHF Study Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe association between sex and long-term outcome in patients hospitalized for acute decompensated heart failure (ADHF) has not been fully studied yet in Japanese population. The aim of this study was to determine differences in baseline characteristics and management of patients with ADHF between women and men and to compare 1-year outcomes between the sexes in a large-scale database representing the current real-world clinical practice in Japan. METHODS AND

resultsKyoto Congestive Heart Failure registry is a prospective cohort study enrolling consecutive patients hospitalized for ADHF in Japan among 19 centres. Baseline characteristics, clinical presentation, management, and 1-year outcomes were compared between men and women. A total of 3728 patients who were alive at discharge constituted the current study population. There were 1671 women (44.8%) and 2057 men. Women were older than men [median (IQR): 83 (76-88) years vs. 77 (68-84) years, P < 0.0001]. Hypertensive and valvular heart diseases were more prevalent in women than in men (28.0% vs. 22.5%, P = 0.0001; and 26.9% vs. 14.0%, P < 0.0001, respectively), whereas ischaemic aetiology was less prevalent in women than in men (20.0% vs. 32.5%, P < 0.0001). Women less often had reduced left ventricular ejection fraction (<40%) than men (27.5% vs. 45.1%, P < 0.0001). The cumulative incidence of all-cause death or hospitalization for heart failure was not significantly different between women and men (33.6% vs. 34.3%, P = 0.71), although women were substantially older than men. After multivariable adjustment, the risk of all-cause death or hospitalization for heart failure was significantly lower among women (adjusted hazard ratio: 0.84, 95% confidence interval: 0.74-0.96, P = 0.01).

conclusionsWomen with heart failure were older and more often presented with preserved EF with a non-ischaemic aetiology and were associated with a reduced adjusted risk of 1-year mortality compared with men in the Japanese population.

Indexed as

Heart FailureSex CharacteristicsFemaleHumansJapanMaleProspective StudiesRegistriesStroke VolumeVentricular Function, LeftHeart failurePrognosisSex difference

Identifiers

PMID32705815
PMCPMC7524241

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.