Evidence map›Paper›PMID 32705780›Full record

GuidelineArthritis & rheumatology (Hoboken, N.J.)2020

American College of Rheumatology Guidance for the Management of Pediatric Rheumatic Disease During the COVID-19 Pandemic: Version 1.

Dawn M Wahezi, Mindy S Lo, Tamar B Rubinstein, Sarah Ringold, Stacy P Ardoin, Kevin J Downes, Karla B Jones, Ronald M Laxer, Rebecca Pellet Madan, Amy S Mudano and 3 more

Open access · hybridAbstract readPractice Guideline
In one paragraph

Guideline in Arthritis & rheumatology (Hoboken, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. COVID-19 in Pediatrics.Rheumatic diseases clinics of North America · 2021
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020
    Article
  18. SARS-CoV-2 infections in children and young people.Clinical immunology (Orlando, Fla.) · 2020
    Review
  19. Pediatric inflammatory multisystem syndrome temporally associated with COVID-19: a spectrum of diseases with many names.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 2 countries.

Dawn M WaheziChildren's Hospital at Montefiore and Albert Einstein College of Medicine, New York, New York.ORCID 0000-0002-0543-7805
Mindy S LoBoston Children's Hospital and Harvard Medical School, Boston, Massachusetts.ORCID 0000-0003-2328-3536
Tamar B RubinsteinChildren's Hospital at Montefiore and Albert Einstein College of Medicine, New York, New York.ORCID 0000-0001-8170-9377
Sarah RingoldSeattle Children's Hospital, Seattle, Washington.ORCID 0000-0001-8660-0207
Stacy P ArdoinNationwide Children's Hospital and Ohio State University, Columbus, Ohio.
Kevin J DownesChildren's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Karla B JonesNationwide Children's Hospital and Ohio State University, Columbus, Ohio.
Ronald M LaxerUniversity of Toronto and The Hospital for Sick Children, Toronto, Ontario, Canada.
Rebecca Pellet MadanNew York University Grossman School of Medicine and Hassenfeld Children's Hospital, New York, New York.
Amy S MudanoUniversity of Alabama at Birmingham.
Amy S TurnerAmerican College of Rheumatology, Atlanta, Georgia.
David R KarpUniversity of Texas Southwestern Medical Center, Dallas.ORCID 0000-0002-9005-1690
Jay J MehtaChildren's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.ORCID 0000-0003-1739-9639
Albert Einstein College of Medicine · USChildren's Hospital of Philadelphia · USNationwide Children's Hospital · USAmerican College of Rheumatology · USBoston Children's Hospital · USNew York University · USSeattle Children's Hospital · USThe University of Texas Southwestern Medical Center · USUniversity of Alabama at Birmingham · USUniversity of Toronto · CA

Funding

Optimizing Vancomycin Therapy in ChildrenK23HD091365 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI DOWNES, KEVIN JAMES · 2018 to 2022
$747k
NICHD NIH HHS K23 HD091365
6 · The paper itself

Abstract

objectiveTo provide clinical guidance to rheumatology providers who treat children with pediatric rheumatic disease (PRD) in the context of the coronavirus disease 2019 (COVID-19) pandemic.

methodsThe task force, consisting of 7 pediatric rheumatologists, 2 pediatric infectious disease physicians, 1 adult rheumatologist, and 1 pediatric nurse practitioner, was convened on May 21, 2020. Clinical questions and subsequent guidance statements were drafted based on a review of the queries posed by the patients as well as the families and healthcare providers of children with PRD. An evidence report was generated and disseminated to task force members to assist with 3 rounds of asynchronous, anonymous voting by email using a modified Delphi approach. Voting was completed using a 9-point numeric scoring system with predefined levels of agreement (categorized as disagreement, uncertainty, or agreement, with median scores of 1-3, 4-6, and 7-9, respectively) and consensus (categorized as low, moderate, or high). To be approved as a guidance statement, median vote ratings were required to fall into the highest tertile for agreement, with either moderate or high levels of consensus.

resultsThe task force drafted 33 guidance statements, which were voted upon during the second and third rounds of voting. Of these 33 statements, all received median vote ratings within the highest tertile of agreement and were associated with either moderate consensus (n = 6) or high consensus (n = 27). Statements with similar recommendations were combined, resulting in 27 final guidance statements.

conclusionThese guidance statements have been generated based on review of the available literature, indicating that children with PRD do not appear to be at increased risk for susceptibility to SARS-CoV-2 infection. This guidance is presented as a "living document," recognizing that the literature on COVID-19 is rapidly evolving, with future updates anticipated.

Indexed as

COVID-19Antirheumatic AgentsChildConsensusHumansPandemicsRheumatic DiseasesAntirheumatic Agents

Identifiers

PMID32705780
PMCPMC7404941
OpenAlexW3043850009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.