ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2021
Preservation of hepatic branch of the vagus nerve reduces the risk of gallstone formation after gastrectomy.
Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Korean Practice Guidelines for Gastric Cancer 2024: An Evidence-based, Multidisciplinary Approach (Update of 2022 Guideline).Journal of gastric cancer · 2025Guideline
- Prophylactic cholecystectomy: A valuable treatment strategy for cholecystolithiasis after gastric cancer surgery.Frontiers in oncology · 2022Pooled it
- A new technique for treating hiatal hernia with gastroesophageal reflux disease: the laparoscopic total left-side surgical approach.BMC surgery · 2021Trial
- Impact of concomitant cholecystectomy during gastrectomy for gastric cancer on the postoperative quality of life.Surgery today · 2026Article
- Incidence and risk factors for symptomatic gallstone disease after gastrectomy for gastric cancer: a nationwide population-based study.International journal of surgery (London, England) · 2026Article
- Modified laparoscopic Toupet fundoplication with vagus nerve sparing via total left-side approach for hiatal hernia with gastroesophageal reflux disease: a pilot study.Translational gastroenterology and hepatology · 2026Article
- Fluorescence Guided Surgery in Gastric Cancer: What Do We Have and What Can We Do?Annals of gastroenterological surgery · 2025Review
- The current landscape and advances in functional-preserving gastric cancer surgery.World journal of surgical oncology · 2025Review
- Current status, trends, and controversies in the selection of gastrectomy procedures: Insights from two nationwide questionnaire surveys conducted over a 7-year interval in Japan.Annals of gastroenterological surgery · 2025Article
- Incidence of Gallstones in Patients with Obesity After Bariatric Surgery in Northern Saudi Arabia: A Cross-Sectional Study.Clinics and practice · 2025Article
- Controversies and consensus surrounding laparoscopic pylorus-preserving gastrectomy for early gastric cancer.World journal of gastrointestinal surgery · 2025Review
- Influence of previous gastrectomy on postoperative bile leakage after laparoscopic liver resection.BMC surgery · 2025Article
- Impact of distal or pylorus preserving gastrectomy on postoperative quality of life in T1 stage middle third gastric cancer patients.Scientific reports · 2025Article
- Bi-phase CT radiomics nomogram for the preoperative prediction of pylorus lymph node metastasis in non-pyloric gastric cancer patients.Abdominal radiology (New York) · 2025Article
- Gallstone Ileus in a 25-Year-Old Female With Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: A Case Report.Case reports in gastrointestinal medicine · 2025Article
- Gallstones after bariatric surgery: mechanisms and prophylaxis.Frontiers in surgery · 2025Review
- Vagus nerve preservation and double-flap technique in laparoscopic proximal gastrectomy.Frontiers in surgery · 2025Article
- Metabolic Crosstalk between Liver and Brain: From Diseases to Mechanisms.International journal of molecular sciences · 2024Review
- Preservation of the celiac branch of the vagus nerve reduces the incidence of postoperative diarrhea in gastric cancer: a cohort study.World journal of surgical oncology · 2024Article
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Authors and funding
13 authors.
Funding
Abstract
backgroundInjury to the vagus nerve has been proposed to be associated with occurrence of gallstones after gastrectomy. We investigated the effect of preservation of hepatic branch of the vagus nerve on prevention of gallstones during laparoscopic distal (LDG) and pylorus-preserving gastrectomy (LPPG).
methodsPreservation of the vagus nerve was reviewed of cT1N0M0 gastric cancer patients underwent LDG (n = 323) and LPPG (n = 144) during 2016-2017. Presence of gallstones was evaluated by ultrasonography (US) and computed tomography (CT). Incidences of gallstones were compared between the nerve preserved (h-DG, h-PPG) group and sacrificed (s-DG, s-PPG) group. Clinicopathological features were also compared.
resultsThe 3-year cumulative incidence of gallstones was lower in the h-DG (2.7%, n = 85) than the s-DG (14.6%, n = 238) (p = 0.017) and lower in the h-PPG (1.6%, n = 123) than the s-PPG (12.9%, n = 21) (p = 0.004). Overall postoperative complication rate was similar between the h-DG and s-DG (p = 0.861) as well as between the h-PPG and s-PPG (p = 0.768). The number of retrieved lymph nodes station #1 and 3-year recurrence-free survival were not significantly different between the preserved group and sacrificed group. Injury to the vagus nerve (p = 0.001) and high body mass index (BMI) (≥ 27.5 kg/m
conclusionsPreservation of hepatic branch of the vagus nerve can be recommended for LDG as well as LPPG of early gastric cancer patients to reduce postoperative gallstone formation.
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