Evidence map›Paper›PMID 32704617›Full record

ArticleJNCI cancer spectrum2020

Relationship of Cisplatin-Related Adverse Health Outcomes With Disability and Unemployment Among Testicular Cancer Survivors.

Sarah L Kerns, Chunkit Fung, Sophie D Fossa, Paul C Dinh, Patrick Monahan, Howard D Sesso, Robert D Frisina, Darren R Feldman, Robert J Hamilton, David Vaughn and 7 more

Open access · goldAbstract read
In one paragraph

Article in JNCI cancer spectrum, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Long-term side effects of testicular cancer and treatment (observational study of mortality and morbidity in testicular cancer survivors).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Observational
  6. Review
  7. Article
  8. Article
  9. Review
  10. Use of Medications for Treating Anxiety or Depression among Testicular Cancer Survivors: A Multi-Institutional Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Observational
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 4 countries.

Sarah L KernsUniversity of Rochester Medical Center, Rochester, NY, USA.ORCID 0000-0002-6503-0011
Chunkit FungUniversity of Rochester Medical Center, Rochester, NY, USA.ORCID 0000-0002-9384-0732
Sophie D FossaOslo University Hospital, Oslo, Norway.ORCID 0000-0002-3729-2217
Paul C DinhIndiana University, Indianapolis, IN, USA.
Patrick MonahanIndiana University, Indianapolis, IN, USA.
Howard D SessoBrigham and Women's Hospital, Boston, MA, USA.
Robert D FrisinaUniversity of South Florida, Tampa, FL, USA.ORCID 0000-0002-7423-6257
Darren R FeldmanMemorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0003-2424-4635
Robert J HamiltonPrincess Margaret Cancer Center, Toronto, Canada.
David VaughnUniversity of Pennsylvania, Philadelphia, PA, USA.
Neil MartinDana-Farber Cancer Institute, Boston, MA, USA.
Robert HuddartRoyal Marsden Hospital, London, UK.ORCID 0000-0003-3604-1990
Christian KollmannsbergerUniversity of British Columbia, Vancouver, British Columbia, Canada.
Deepak SahasrabudheUniversity of Rochester Medical Center, Rochester, NY, USA.
Shirin Ardeshir-Rouhani-FardIndiana University, Indianapolis, IN, USA.ORCID 0000-0003-0105-0301
Lawrence EinhornIndiana University, Indianapolis, IN, USA.
Lois B TravisIndiana University, Indianapolis, IN, USA.
Indiana University – Purdue University Indianapolis · USUniversity of Rochester Medical Center · USBrigham and Women's Hospital · USDana-Farber Cancer Institute · USMemorial Sloan Kettering Cancer Center · USOslo University Hospital · NOPrincess Margaret Cancer Centre · CARoyal Marsden Hospital · GBUniversity of British Columbia · CAUniversity of Pennsylvania · USUniversity of South Florida · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Genetic Susceptibility and Biomarkers of Platinum-related ToxicitiesR01CA157823 · NCI · UNIVERSITY OF ROCHESTER · PI TRAVIS, LOIS B. · 2012 to 2025
$11.2M
Risk Prediction for Development of Adverse Effects FOllowing Radiotherapy for Prostate CancerK07CA187546 · NCI · UNIVERSITY OF ROCHESTER · PI KERNS, SARAH L. · 2015 to 2019
$649k
NCI NIH HHS K07 CA187546NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA157823
6 · The paper itself

Abstract

backgroundFew data exist on the relationship of cisplatin-related adverse health outcomes (AHOs) with disability, unemployment, and self-reported health (SRH) among testicular cancer survivors (TCS).

methodsA total of 1815 TCS at least 1 year postchemotherapy underwent clinical examination and completed questionnaires. Treatment data were abstracted from medical records. A cumulative burden of morbidity score (CBM

resultsAlmost 1 in 10 TCS was out of work (2.4%, disability leave; 6.8%, unemployed) at a median age of 37 years (median follow-up = 4 years). PSN (odds ratio [OR] = 2.89, 95% confidence interval [CI] = 1.01 to 8.26, grade 3 vs 0,

conclusionsOur findings have important implications regarding treatment-associated productivity losses and socioeconomic costs in this young population. Survivorship care strategies should include inquiries about disability and unemployment status, with efforts made to assist affected TCS in returning to the workforce.

Identifiers

PMID32704617
PMCPMC7368467
OpenAlexW3011055919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.