Evidence map›Paper›PMID 32704550›Full record

ArticleEndocrinology, diabetes & metabolism2020

The effectiveness of insulin glargine 300 U/mL among type 2 diabetes patients: Analysis of a real-world data in Israel.

Cheli Melzer Cohen, Tamar Banon, Varda Shalev, Gabriel Chodick

Abstract read
In one paragraph

Article in Endocrinology, diabetes & metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cheli Melzer CohenMaccabi Institute for Research and Innovation Maccabi Healthcare Services Tel Aviv Israel.ORCID https://orcid.org/0000-0001-9033-4108
Tamar BanonMaccabi Institute for Research and Innovation Maccabi Healthcare Services Tel Aviv Israel.
Varda ShalevMaccabi Institute for Research and Innovation Maccabi Healthcare Services Tel Aviv Israel.
Gabriel ChodickMaccabi Institute for Research and Innovation Maccabi Healthcare Services Tel Aviv Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsRandomized controlled trials have shown that insulin glargine 300 U/mL (Gla-300) has a more stable and prolonged glucose lowering effect among patients with type 2 diabetes (T2DM) compared to insulin glargine 100 U/mL (Gla-100), resulting in a reduced risk of hypoglycaemia while maintaining a similar efficacy of lowering HbA MATERIAL AND

methodsIn this retrospective cohort study, data from a large state-mandated health organization were used to identify adult T2DM patients who were previously on insulin and initiated Gla-300 therapy between 6/ 2016 and 12/2017. Changes in HbA

resultsA total of 1797 patients were included in this study with a mean age of 64.2 (SD = ±11.0y), baseline HbA

conclusionsThis real-world study supports evidence from RCTs regarding the effectiveness of Gla-300 among T2DM patients by improving glycaemic control.

Indexed as

basal insulinglargine‐300observational studytype 2 diabetes mellitus

Identifiers

PMID32704550
PMCPMC7375096

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.