Evidence map›Paper›PMID 32704420›Full record

SynthesisTranslational vision science & technology2020

Introduction to Machine Learning, Neural Networks, and Deep Learning.

Rene Y Choi, Aaron S Coyner, Jayashree Kalpathy-Cramer, Michael F Chiang, J Peter Campbell

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 551 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
551citing papers in PubMed, 14 pooled it
48.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

551 citing papers in PubMed, 14 syntheses or guidelines pooled it, 984 citations in OpenAlex.

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  3. Guideline
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  14. Moving towards the use of artificial intelligence in pain management.European journal of pain (London, England) · 2025
    Pooled it
  15. Review
  16. Article
  17. Article
  18. Review
  19. Machine learning-based screening tool for predicting the risk of oropharyngeal dysphagia in patients with ischemic stroke.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  20. Artificial Intelligence for Esophageal Precancerous Lesions and Esophageal Cancer.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Review

491 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rene Y ChoiDepartment of Ophthalmology, Casey Eye Institute, Oregon Health & Science University (OHSU), Portland, Oregon, United States.
Aaron S CoynerDepartment of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, Oregon, United States.
Jayashree Kalpathy-CramerAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, United States.
Michael F ChiangDepartment of Ophthalmology, Casey Eye Institute, Oregon Health & Science University (OHSU), Portland, Oregon, United States.
J Peter CampbellDepartment of Ophthalmology, Casey Eye Institute, Oregon Health & Science University (OHSU), Portland, Oregon, United States.
Oregon Health & Science University · USMassachusetts General Hospital · US

Funding

TRAINING PROGRAM IN HEALTH INFORMATICST15LM007088 · NLM · OREGON HEALTH & SCIENCE UNIVERSITY · PI WILLIAM R HERSH, Vishnu Mohan · 1992 to 2026
$23.4M
Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI John Peter Campbell · 1995 to 2026
$19.4M
Clinical and Genetic Analysis of Retinopathy of PrematurityR01EY019474 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI CAMPBELL, JOHN PETER · 2010 to 2020
$7.0M
Mentored Vision Clinician-Scientist Program at OHSUK12EY027720 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI David Huang · 2018 to 2026
$2.2M
Clinical and genetic analysis of retinopathy of prematurityR01HD107493 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI CAMPBELL, JOHN PETER · 2021 to 2023
$1.8M
NEI NIH HHS K12 EY027720NEI NIH HHS P30 EY010572NEI NIH HHS R01 EY019474NICHD NIH HHS R01 HD107493NLM NIH HHS T15 LM007088
6 · The paper itself

Abstract

Purpose: To present an overview of current machine learning methods and their use in medical research, focusing on select machine learning techniques, best practices, and deep learning. Methods: A systematic literature search in PubMed was performed for articles pertinent to the topic of artificial intelligence methods used in medicine with an emphasis on ophthalmology. Results: A review of machine learning and deep learning methodology for the audience without an extensive technical computer programming background. Conclusions: Artificial intelligence has a promising future in medicine; however, many challenges remain. Translational Relevance: The aim of this review article is to provide the nontechnical readers a layman's explanation of the machine learning methods being used in medicine today. The goal is to provide the reader a better understanding of the potential and challenges of artificial intelligence within the field of medicine.

Indexed as

Deep LearningMachine LearningOphthalmologyArtificial IntelligenceNeural Networks, Computerartificial intelligencedeep learningmachine learning

Identifiers

PMID32704420
PMCPMC7347027
OpenAlexW3009207988

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.