Evidence map›Paper›PMID 32704411›Full record

ReviewTranslational vision science & technology2020

Artificial Intelligence in Retinopathy of Prematurity Diagnosis.

Brittni A Scruggs, R V Paul Chan, Jayashree Kalpathy-Cramer, Michael F Chiang, J Peter Campbell

Open access · goldAbstract readReview
In one paragraph

Review in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 86 citations in OpenAlex.

  1. Pooled it
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  12. Establishing an objective quantitative method for assessing the severity of plus disease in retinopathy of prematurity.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  13. Stakeholder Attitudes on AI Integration in Ophthalmology.Klinische Monatsblatter fur Augenheilkunde · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Brittni A ScruggsCasey Eye Institute, Department of Ophthalmology, Oregon Health & Science University, Portland, OR, USA.
R V Paul ChanDepartment of Ophthalmology, University of Illinois, Chicago, IL, USA.
Jayashree Kalpathy-CramerAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
Michael F ChiangCasey Eye Institute, Department of Ophthalmology, Oregon Health & Science University, Portland, OR, USA.
J Peter CampbellCasey Eye Institute, Department of Ophthalmology, Oregon Health & Science University, Portland, OR, USA.
Oregon Health & Science University · USAthinoula A. Martinos Center for Biomedical Imaging · USUniversity of Illinois Chicago · US

Funding

Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI John Peter Campbell · 1995 to 2026
$19.4M
Clinical and Genetic Analysis of Retinopathy of PrematurityR01EY019474 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI CAMPBELL, JOHN PETER · 2010 to 2020
$7.0M
Mentored Vision Clinician-Scientist Program at OHSUK12EY027720 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI David Huang · 2018 to 2026
$2.2M
Clinical and genetic analysis of retinopathy of prematurityR01HD107493 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI CAMPBELL, JOHN PETER · 2021 to 2023
$1.8M
NEI NIH HHS K12 EY027720NEI NIH HHS P30 EY010572NEI NIH HHS R01 EY019474NICHD NIH HHS R01 HD107493
6 · The paper itself

Abstract

Retinopathy of prematurity (ROP) is a leading cause of childhood blindness worldwide. The diagnosis of ROP is subclassified by zone, stage, and plus disease, with each area demonstrating significant intra- and interexpert subjectivity and disagreement. In addition to improved efficiencies for ROP screening, artificial intelligence may lead to automated, quantifiable, and objective diagnosis in ROP. This review focuses on the development of artificial intelligence for automated diagnosis of plus disease in ROP and highlights the clinical and technical challenges of both the development and implementation of artificial intelligence in the real world.

Indexed as

Artificial IntelligenceRetinopathy of PrematurityChildHumansInfant, Low Birth WeightInfant, Newbornartificial intelligencemachine learningpediatric retinaretinopathy of prematurity

Identifiers

PMID32704411
PMCPMC7343673
OpenAlexW3001006670

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.