ArticleVeterinary record open2020
C-reactive protein in dogs with suspected bacterial diskospondylitis: 16 cases (2010-2019).
Article in Veterinary record open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Treatment of discospondylitis in dogs: A systematic review.The Veterinary record · 2026Pooled it
- First Description of Atypical Aspergillus floccosus as Cause of Canine Systemic Aspergillosis With Discospondylitis.Veterinary medicine and science · 2025Article
- Clinical presentation, treatment, and outcome of 24 dogs with bacterial meningitis or meningoencephalitis without empyema (2010-2020).Journal of veterinary internal medicine · 2023Article
- Clinical Presentation, MRI Characteristics, and Outcome of Conservative or Surgical Management of Spinal Epidural Empyema in 30 Dogs.Animals : an open access journal from MDPI · 2022Article
- Bayesian clinical reasoning in the first opinion approach to a dog with suspected thoracolumbar pain.The Journal of small animal practice · 2022Review
- C-Reactive Protein as a Diagnostic Marker in Dogs: A Review.Animals : an open access journal from MDPI · 2022Review
- Clinical features, treatment and outcome of discospondylitis in cats.Journal of feline medicine and surgery · 2022Article
- Clinical Signs, Advanced Diagnostic Imaging Findings, Treatment, and Outcome of Mycotic Discospondylitis in 11 Dogs.Journal of veterinary internal medicineArticle
- Multifocal discospondylitis and osteomyelitis due toJFMS open reportsArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesC-reactive protein (CRP) is an acute phase protein used in multiple canine inflammatory conditions including steroid responsive meningitis-arteritis, immune-mediated polyarthritis and bronchopneumonia. The aim of this study was to assess whether serum CRP is elevated in cases of diskospondylitis.
methodsMedical records from 2010 to 2019 were searched to identify dogs diagnosed with diskospondylitis based on findings consistent on CT or MRI and with CRP tested.
resultsA total of 16 dogs met the inclusion criteria. All cases had back pain. Fourteen cases had elevated CRP, with a median value of 100.7 mg/l (reference range for CRP values: 0-10 mg/l), 12 were pyrexic and six had leucocytosis. The two dogs with normal CRP were normothermic and did not have leucocytosis. CRP was measured four to six weeks into antimicrobial treatment in eight of 14 dogs and was normal in all cases. One dog developed a suspected bacterial empyema diagnosed on MRI; this occurred two weeks after antibiotic treatment was discontinued based on a normal CRP level at follow-up.
conclusionsSerum CRP is elevated in cases of diskospondylitis and may be clinically more useful to screen dogs with back pain than pyrexia or leucocytosis alone. Further long-term clinical evaluation in a prospective study is needed to assess its use as a treatment monitoring tool and in decision making.
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