ArticleLight, science & applications2020
Infrared chemical imaging through non-degenerate two-photon absorption in silicon-based cameras.
Article in Light, science & applications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 50 citations in OpenAlex.
- Mid-infrared snapshot spectral imaging via nonlinear radial dispersion.Nature communications · 2026Article
- Enantio-selective vibronic coupling revealed via dissymmetry of upconverted emission in double-resonance excitation of chiral polymer.Nature communications · 2025Article
- Single-Molecule Vibrational Thermometry.The journal of physical chemistry. B · 2025Article
- Predictive Modeling of Lignocellulosic Content in Crop Straws Using NIR Spectroscopy.Plants (Basel, Switzerland) · 2025Article
- Mid-infrared hyperspectral microscopy with broadband 1-GHz dual frequency combs.APL photonics · 2024Article
- Vibrational imaging of metabolites for improved microbial cell strains.Journal of biomedical optics · 2024Review
- Cryogenic Single-Molecule Fluorescence Detection of the Mid-Infrared Response of an Intrinsic Pigment in a Light-Harvesting Complex.The journal of physical chemistry. B · 2023Article
- Spectral imaging at high definition and high speed in the mid-infrared.Science advances · 2022Article
- Wide-field mid-infrared single-photon upconversion imaging.Nature communications · 2022Article
- Design Considerations for Discrete Frequency Infrared Microscopy Systems.Applied spectroscopy · 2021Article
- High-speed 2D and 3D mid-IR imaging with an InGaAs camera.APL photonics · 2021Article
- Article
- Bond-selective imaging by optically sensing the mid-infrared photothermal effect.Science advances · 2021Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Chemical imaging based on mid-infrared (MIR) spectroscopic contrast is an important technique with a myriad of applications, including biomedical imaging and environmental monitoring. Current MIR cameras, however, lack performance and are much less affordable than mature Si-based devices, which operate in the visible and near-infrared regions. Here, we demonstrate fast MIR chemical imaging through non-degenerate two-photon absorption (NTA) in a standard Si-based charge-coupled device (CCD). We show that wide-field MIR images can be obtained at 100 ms exposure times using picosecond pulse energies of only a few femtojoules per pixel through NTA directly on the CCD chip. Because this on-chip approach does not rely on phase matching, it is alignment-free and does not necessitate complex postprocessing of the images. We emphasize the utility of this technique through chemically selective MIR imaging of polymers and biological samples, including MIR videos of moving targets, physical processes and live nematodes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.