Evidence map›Paper›PMID 32704224›Full record

ArticleJournal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America2019

Flexible and Interpretable Models for Survival Data.

Jiacheng Wu, Daniela Witten

Abstract read
In one paragraph

Article in Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Interpretable Machine Learning for Survival Analysis.Biometrical journal. Biometrische Zeitschrift · 2025
    Review
  3. Article
  4. Survival Mixture Density Networks.Proceedings of machine learning research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jiacheng WuDepartment of Biostatistics, University of Washington, Seattle, WA.
Daniela WittenDepartment of Biostatistics, University of Washington, Seattle, WA.

Funding

High-dimensional unsupervised learning, with applications to genomicsDP5OD009145 · OD · UNIVERSITY OF WASHINGTON · PI WITTEN, DANIELA · 2011 to 2015
$1.8M
NIH HHS DP5 OD009145
6 · The paper itself

Abstract

As datasets continue to increase in size, there is growing interest in methods for prediction that are both Received January 2018 flexible and interpretable. A flurry of recent work on this topic has focused on additive modeling in the Revised February 2019 regression setting, and in particular, on the use of data-adaptive nonlinear functions that can be used to flexibly model each covariate's effect, conditional on the other features in the model. In this article, we extend this recent line of work to the survival setting. We develop an additive Cox proportional hazards model, in which each additive function is obtained by trend filtering, so that the fitted functions are piece-wise polynomial with adaptively chosen knots. An efficient proximal gradient descent algorithm is used to fit the model. We demonstrate its performance in simulations and in application to a primary biliary cirrhosis data set, as well as a dataset consisting of time to publication for clinical trials in the biomedical literature. Supplementary materials for this article are available online.

Indexed as

Additive modelCox’s modelPiece-wise polynomialTrend filtering

Identifiers

PMID32704224
PMCPMC7377334

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.