Evidence map›Paper›PMID 32703938›Full record

ArticleCell death & disease2020

p53 isoform Δ113p53 promotes zebrafish heart regeneration by maintaining redox homeostasis.

Shengfan Ye, Ting Zhao, Wei Zhang, Zimu Tang, Ce Gao, Zhipeng Ma, Jing-Wei Xiong, Jinrong Peng, Wei-Qiang Tan, Jun Chen

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

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  9. Journal of cardiovascular development and disease · 2023
    Article
  10. Energy metabolism homeostasis in cardiovascular diseases.Journal of geriatric cardiology : JGC · 2021
    Article
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Shengfan Ye *MOE Key Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, 310058, Hangzhou, China.
Ting Zhao *MOE Key Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, 310058, Hangzhou, China.
Wei ZhangMOE Key Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, 310058, Hangzhou, China.
Zimu TangMOE Key Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, 310058, Hangzhou, China.
Ce GaoCollege of Animal Sciences, Zhejiang University, 310058, Hangzhou, China.
Zhipeng MaMOE Key Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, 310058, Hangzhou, China.
Jing-Wei XiongInstitute of Molecular Medicine, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, 100871, Beijing, China.
Jinrong PengCollege of Animal Sciences, Zhejiang University, 310058, Hangzhou, China.
Wei-Qiang TanDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 3 Qingchun Road East, 310016, Hangzhou, China. tanweixxxx@zju.edu.cn.ORCID http://orcid.org/0000-0003-4951-0960
Jun ChenMOE Key Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, 310058, Hangzhou, China. chenjun2009@zju.edu.cn.
Zhejiang University · CNPeking University · CNSir Run Run Shaw Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal mice and adult zebrafish can fully regenerate their hearts through proliferation of pre-existing cardiomyocytes. Previous studies have revealed that p53 signalling is activated during cardiac regeneration in neonatal mice and that hydrogen peroxide (H

Indexed as

HomeostasisAnimalsAntioxidantsApoptosisCell MovementCell ProliferationGATA4 Transcription FactorHeartHydrogen PeroxideMutationMyocytes, CardiacOxidation-ReductionProtein IsoformsRegenerationTumor Suppressor Protein p53Up-RegulationAntioxidantsGATA4 Transcription FactorHydrogen PeroxideProtein IsoformsTumor Suppressor Protein p53

Identifiers

PMID32703938
PMCPMC7378207
OpenAlexW3044679416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.