Evidence map›Paper›PMID 32703847›Full record

ArticleScience (New York, N.Y.)2020

Simultaneous cross-evaluation of heterogeneous

Derek N Macklin, Travis A Ahn-Horst, Heejo Choi, Nicholas A Ruggero, Javier Carrera, John C Mason, Gwanggyu Sun, Eran Agmon, Mialy M DeFelice, Inbal Maayan and 11 more

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 159 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Contributions of intra- and extracellular antibiotic degradation to collective [Formula: see text]-lactam survival.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
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  8. A NovelbioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Compartment-guided assembly of large-scale molecular models with Bentopy.Protein science : a publication of the Protein Society · 2026
    Article
  11. Article
  12. Article
  13. The EcoCyc database (2025).EcoSal Plus · 2025
    Review
  14. Integrative mapping reveals molecular features underlying the mechanism of nucleocytoplasmic transport.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Beyond evolution:Biosafety and health · 2025
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 2 institutions in 1 country.

Derek N Macklin *Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-7257-0315
Travis A Ahn-Horst *Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-3049-3366
Heejo Choi *Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-2848-0267
Nicholas A Ruggero *Allen Discovery Center at Stanford University, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-5034-9716
Javier Carrera *Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
John C Mason *Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-4289-7464
Gwanggyu SunDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-2649-7807
Eran AgmonDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-1279-2474
Mialy M DeFeliceDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-7197-6292
Inbal MaayanDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-4907-0723
Keara LaneDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Ryan K SpanglerDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Taryn E GilliesDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0001-6223-9357
Morgan L PaullDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0001-6852-1636
Sajia AkhterDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-0793-0625
Samuel R BrayDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-9696-6920
Daniel S WeaverSRI International, Menlo Park, CA 94025, USA.ORCID 0000-0002-2906-3019
Ingrid M KeselerSRI International, Menlo Park, CA 94025, USA.ORCID 0000-0003-1738-6117
Peter D KarpSRI International, Menlo Park, CA 94025, USA.ORCID 0000-0002-5876-6418
Jerry H MorrisonAllen Discovery Center at Stanford University, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0001-9414-6999
Markus W CovertDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA. mcovert@stanford.edu.ORCID 0000-0002-5993-8912
Stanford University · USSRI International · US

Funding

The EcoCyc Model Organism Database for Escherichia coli [SRI Proposal ECU 14-631]U24GM077678 · NIGMS · SRI INTERNATIONAL · PI KARP, PETER D · 2006 to 2018
$12.3M
TRAINING & OUTREACH COREP50GM107615 · NIGMS · STANFORD UNIVERSITY · PI FERRELL, JAMES E. · 2013 to 2017
$10.9M
The EcoCyc Model Organism Database for Escherichia coliR01GM077678 · NIGMS · SRI INTERNATIONAL · PI KARP, PETER D · 2019 to 2022
$4.6M
A Gene-Complete Computational Model of YeastDP1OD006413 · OD · STANFORD UNIVERSITY · PI COVERT, MARKUS W · 2009 to 2011
$2.4M
A Gene-Complete Computational Model of YeastDP1LM011510 · NLM · STANFORD UNIVERSITY · PI COVERT, MARKUS W · 2012 to 2013
$1.6M
Deep Curation via an Integrated Whole-Cell Computational ModelR01LM013229 · NLM · STANFORD UNIVERSITY · PI COVERT, MARKUS W · 2020 to 2023
$1.5M
NIGMS NIH HHS P50 GM107615NIGMS NIH HHS R01 GM077678NIGMS NIH HHS U24 GM077678NIH HHS DP1 OD006413NLM NIH HHS DP1 LM011510NLM NIH HHS R01 LM013229
6 · The paper itself

Abstract

The extensive heterogeneity of biological data poses challenges to analysis and interpretation. Construction of a large-scale mechanistic model of

Indexed as

Data AnalysisDatasets as TopicEscherichia coliEscherichia coli ProteinsComputer SimulationEscherichia coli Proteins

Identifiers

PMID32703847
PMCPMC7990026
OpenAlexW3044339796

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.