Evidence map›Paper›PMID 32703806›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Molecular characterization of a fungal gasdermin-like protein.

Asen Daskalov, Patrick S Mitchell, Andrew Sandstrom, Russell E Vance, N Louise Glass

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 84 citations in OpenAlex.

  1. The gasdermin family: from pyroptosis mechanisms to therapeutic targets.Signal transduction and targeted therapy · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Unanticipated Loss of Inflammasomes in Birds.Genome biology and evolution · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. mSphere · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Asen DaskalovPlant and Microbial Biology Department, University of California, Berkeley, CA 94720; asen.daskalov@u-bordeaux.fr Lglass@berkeley.edu.ORCID 0000-0002-9394-8962
Patrick S MitchellDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.ORCID 0000-0001-8375-9060
Andrew SandstromHoward Hughes Medical Institute, University of California, Berkeley, CA 94720.ORCID 0000-0002-8629-9087
Russell E VanceDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.ORCID 0000-0002-6686-3912
N Louise GlassPlant and Microbial Biology Department, University of California, Berkeley, CA 94720; asen.daskalov@u-bordeaux.fr Lglass@berkeley.edu.ORCID 0000-0002-4844-2890
Howard Hughes Medical Institute · USUniversity of California, Berkeley · USLawrence Berkeley National Laboratory · US

Funding

Functional and Structural Dissection of Inflammasome ActivationR37AI075039 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI RUSSELL E VANCE · 2018 to 2026
$3.8M
ANALYSIS OF PROGRAMMED CELL DEATH IN FILAMENTOUS FUNGIR01GM060468 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI GLASS, N LOUISE · 2000 to 2014
$3.6M
Dissection of Shigella pathogenesis in vivo using a new oral infection mouse modelR01AI155634 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI VANCE, RUSSELL E · 2020 to 2024
$2.2M
NIAID NIH HHS R01 AI155634NIAID NIH HHS R37 AI075039NIGMS NIH HHS R01 GM060468
6 · The paper itself

Abstract

Programmed cell death (PCD) in filamentous fungi prevents cytoplasmic mixing following fusion between conspecific genetically distinct individuals (allorecognition) and serves as a defense mechanism against mycoparasitism, genome exploitation, and deleterious cytoplasmic elements (i.e., senescence plasmids). Recently, we identified

Indexed as

Fungal ProteinsNeoplasm ProteinsHEK293 CellsHumansImmunity, InnateNeurospora crassaPyroptosisFungal ProteinsNeoplasm Proteinsgasdermininnate immunityNeurosporaprogrammed cell deathpyroptosis

Identifiers

PMID32703806
PMCPMC7414189
OpenAlexW3043910918

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.