Evidence map›Paper›PMID 32703663›Full record

ArticleAnnals of epidemiology2020

Excessive gestational weight gain is associated with severe maternal morbidity.

Kyle E Freese, Katherine P Himes, Jennifer A Hutcheon, Sara M Parisi, Maria M Brooks, Kathleen McTigue, Lisa M Bodnar

Abstract read
In one paragraph

Article in Annals of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kyle E FreeseDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA.
Katherine P HimesDepartment of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA; Magee-Womens Research Institute, Pittsburgh, PA.
Jennifer A HutcheonDepartment of Obstetrics and Gynaecology, University of British Columbia, Vancouver, Canada.
Sara M ParisiDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA.
Maria M BrooksDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA; Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA.
Kathleen McTigueDepartment of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA.
Lisa M BodnarDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA; Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA; Magee-Womens Research Institute, Pittsburgh, PA. Electronic address: bodnar@edc.pitt.edu.

Funding

Innovative Approaches to Inform Evidence-Based Pregnancy Weight Gain GuidelinesR01HD072008 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BODNAR, LISA M, HUTCHEON, JENNIFER ANNE · 2013 to 2016
$2.4M
Innovative approaches to inform evidence-based pregnancy weight gain guidelinesR01HD094777 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BODNAR, LISA M, HUTCHEON, JENNIFER ANNE · 2018 to 2021
$2.1M
NICHD NIH HHS R01 HD072008NICHD NIH HHS R01 HD094777
6 · The paper itself

Abstract

purposeWe determined the association between gestational weight gain and severe maternal morbidity.

methodsWe used data on 84,241 delivery hospitalizations at Magee-Womens Hospital, Pittsburgh, PA (2003-2012). Total gestational weight gain (kilogram) was converted to gestational age-standardized z-scores. We defined severe maternal morbidity as having ≥1 of the 21 Centers for Disease Control diagnosis or procedure codes for severe maternal morbidity identification, intensive care unit admission, or extended postpartum stay. We used multivariable logistic regression to determine the association between weight gain and severe maternal morbidity after confounder adjustment.

resultsHigh gestational weight gain z-scores were associated with an increased risk of severe maternal morbidity. Compared with z-score 0 SD (equivalent to 16 kg at 40 weeks in a normal-weight woman), risk differences (95% confidence intervals) for z-scores -2 SD (7 kg), -1 SD (11 kg), +1 SD (23 kg), and +2 SD (31 kg) were 1.5 (-0.71, 3.7), 0.056 (-0.81, 0.93), 3.4 (1.7, 5.0), and 8.6 (4.0, 13) per 1000 deliveries. The results did not vary by gestational age at delivery or prepregnancy body mass index.

conclusionsThe increased risk of severe maternal morbidity with high pregnancy weight gain may allow scientists to understand and prevent this serious condition.

Indexed as

AdultFemaleGestational Weight GainHeart FailureHumansHypertensionIncidenceMorbidityObesityPennsylvaniaPregnancyPremature BirthGestational weight gainNutritionPregnancySevere maternal morbidity

Identifiers

PMID32703663
PMCPMC7541767

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.