ArticleThe American journal of emergency medicine2021
Is novel coronavirus 2019 reinfection possible? Interpreting dynamic SARS-CoV-2 test results.
Article in The American journal of emergency medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 6 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
57 citing papers in PubMed, 6 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- Clinical manifestations, treatment options, and comorbidities in COVID-19 relapse patients: A systematic review.Journal of clinical laboratory analysis · 2022Pooled it
- SARS-CoV-2 Reinfection Is a New Challenge for the Effectiveness of Global Vaccination Campaign: A Systematic Review of Cases Reported in Literature.International journal of environmental research and public health · 2021Pooled it
- A systematic review on the recurrence of SARS-CoV-2 virus: frequency, risk factors, and possible explanations.Infectious diseases (London, England) · 2021Pooled it
- Characteristics of COVID-19 Recurrence: A Systematic Review and Meta-Analysis.Annals of global health · 2021Pooled it
- Reinfection or Reactivation of Severe Acute Respiratory Syndrome Coronavirus 2: A Systematic Review.Frontiers in public health · 2021Pooled it
- Is recurrence possible in coronavirus disease 2019 (COVID-19)? Case series and systematic review of literature.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Pooled it
- Clinical characteristics associated with recurrent viral RNA positivity in patients within two weeks after recovering from the first SARS-CoV-2 infection.Biomolecules & biomedicine · 2024Article
- Immune landscape and redox imbalance during neurological disorders in COVID-19.Cell death & disease · 2023Review
- Understanding the challenges to COVID-19 vaccines and treatment options, herd immunity and probability of reinfection.Journal of Taibah University Medical Sciences · 2023Review
- Evaluation of possible COVID-19 reinfection in children: A multicenter clinical study.Archives de pediatrie : organe officiel de la Societe francaise de pediatrie · 2023Article
- Longitudinal study of humoral immunity against SARS-CoV-2 of health professionals in Brazil: the impact of booster dose and reinfection on antibody dynamics.Frontiers in immunology · 2023Article
- Pyfectious: An individual-level simulator to discover optimal containment policies for epidemic diseases.PLoS computational biology · 2023Article
- Article
- Clinical and epidemiological features of patients with COVID-19 reinfection: a systematic review.New microbes and new infections · 2022Review
- SARS-CoV-2 reinfection across a spectrum of immunological states.Health science reports · 2022Article
- Transmission dynamics of COVID-19 pandemic with combined effects of relapse, reinfection and environmental contribution: A modeling analysis.Results in physics · 2022Article
- Recurrent viral RNA positivity and candidiasis findings in hospitalized patients with COVID-19.Future microbiology · 2022Article
- The impact of lymphoid memory cells in different ages of COVID-19 patients.Gene reports · 2022Review
- Emerging COVID-19 reinfection four months after primary SARS-CoV-2 infection.Wiener medizinische Wochenschrift (1946) · 2022Article
- Mass spectrometry applied to diagnosis, prognosis, and therapeutic targets identification for the novel coronavirus SARS-CoV-2: A review.Analytica chimica acta · 2022Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since December 2019, COVID-19, the clinical syndrome associated with SARS-CoV-2 infection, has infected more than 6.2 million people and brought the function of the global community to a halt. As the number of patients recovered from COVID-19 rises and the world transitions toward reopening, the question of acquired immunity versus the possibility of reinfection are critical to anticipating future viral spread. Here, we present a case of a patient previously recovered from COVID-19 who re-presents with new respiratory, radiographical, laboratory, and real-time reverse transcriptase-polymerase chain reaction (RT-PCR) findings concerning for possible re-infection. We review this case in the context of the evolving discussion and theories surrounding dynamic RT-PCR results, prolonged viral shedding, and the possibility of developed immunity. Understanding how to interpret dynamic and late-positive SARS-CoV-2 RT-PCR results after primary infection will be critical for understanding disease prevalence and spread among communities worldwide.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.