Evidence map›Paper›PMID 32703440›Full record

ArticleBiochemical and biophysical research communications2020

Transcript decay mediated by RNase III in Borrelia burgdorferi.

Santina Snow, Emily Bacon, Jennifer Bergeron, David Katzman, Amelia Wilhelm, Owen Lewis, Deepsing Syangtan, Andrew Calkins, Linda Archambault, Melissa L Anacker and 1 more

Open access · greenAbstract read
In one paragraph

Article in Biochemical and biophysical research communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Gene Regulation and Transcriptomics.Current issues in molecular biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Santina SnowDepartment of Chemistry and Biochemistry, Bates College, Lewiston, ME, USA.
Emily BaconDepartment of Chemistry and Biochemistry, Bates College, Lewiston, ME, USA.
Jennifer BergeronDepartment of Chemistry and Biochemistry, Bates College, Lewiston, ME, USA.
David KatzmanDepartment of Chemistry and Biochemistry, Bates College, Lewiston, ME, USA.
Amelia WilhelmDepartment of Chemistry and Biochemistry, Bates College, Lewiston, ME, USA.
Owen LewisDepartment of Chemistry and Biochemistry, Bates College, Lewiston, ME, USA.
Deepsing SyangtanDepartment of Chemistry and Biochemistry, Bates College, Lewiston, ME, USA.
Andrew CalkinsDepartment of Chemistry and Biochemistry, Bates College, Lewiston, ME, USA.
Linda ArchambaultDepartment of Chemistry and Biochemistry, Bates College, Lewiston, ME, USA.
Melissa L AnackerDivision of Biological Sciences, University of Montana, Missoula, MT, USA.
Paula Jean SchlaxDepartment of Chemistry and Biochemistry, Bates College, Lewiston, ME, USA. Electronic address: pschlax@bates.edu.
Bates College · USUniversity of Montana · US

Funding

mRNA Degradation in Borrelia burgdorferiR15GM107700 · NIGMS · BATES COLLEGE · PI SCHLAX, PAULA J · 2015 to 2015
$346k
NIGMS NIH HHS R15 GM107700
6 · The paper itself

Abstract

The causative agent of Lyme disease, Borrelia burgdorferi, requires shifts in gene expression to undergo its natural enzootic cycle between tick and vertebrate hosts. mRNA decay mechanisms play significant roles in governing gene expression in other bacteria, but are not yet characterized in B. burgdorferi. RNase III is an important enzyme in processing ribosomal RNA, but it also plays a role in mRNA decay in many bacteria. We compared RNA decay profiles and steady-state abundances of transcripts in wild-type Borrelia burgdorferi strain B31 and in an RNase III null (rnc

Indexed as

RNA StabilityAnimalsBacterial ProteinsBorrelia burgdorferiGene DeletionGene Expression Regulation, BacterialHumansLyme DiseaseRibonuclease IIIRNA, MessengerBacterial ProteinsRibonuclease IIIRNA, MessengerBorrelia burgdorferiLyme diseasemRNA decayRNase III

Identifiers

PMID32703440
PMCPMC7427566
OpenAlexW3038490278

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.