Evidence map›Paper›PMID 32703288›Full record

Trial reportBMC medicine2020

Randomized control trial testing the effectiveness of implemented depression prevention in high-risk adolescents.

Karlijn W J de Jonge-Heesen, Sanne P A Rasing, Ad A Vermulst, Ron H J Scholte, Kim M van Ettekoven, Rutger C M E Engels, Daan H M Creemers

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Karlijn W J de Jonge-HeesenGGZ Oost Brabant, P.O. Box 3, 5427 ZG, Boekel, The Netherlands. kwj.heesen@ggzoostbrabant.nl.
Sanne P A RasingGGZ Oost Brabant, P.O. Box 3, 5427 ZG, Boekel, The Netherlands.
Ad A VermulstGGZ Oost Brabant, P.O. Box 3, 5427 ZG, Boekel, The Netherlands.
Ron H J ScholtePraktikon, P.O. Box 6909, 6503 GK, Nijmegen, The Netherlands.
Kim M van EttekovenGGZ Oost Brabant, P.O. Box 3, 5427 ZG, Boekel, The Netherlands.
Rutger C M E EngelsErasmus School of Social and Behavioural Sciences, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands.
Daan H M CreemersGGZ Oost Brabant, P.O. Box 3, 5427 ZG, Boekel, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdolescent depression is a global mental health concern. Identification and effective prevention in an early stage are necessary. The present randomized, controlled trial aimed to examine the effectiveness of Cognitive Behavioral Therapy (CBT)-based depression prevention in adolescents with elevated depressive symptoms. This prevention approach is implemented in school communities, which allows to examine effects under real-life circumstances.

methodsA total of 5222 adolescents were screened for elevated depressive symptoms in the second grade of secondary schools; 130 adolescents aged between 12 and 16 years old (M = 13.59; SD = 0.68; 63.8% girls) were randomly assigned to the experimental (OVK 2.0) or control condition (psycho-education). Self- and parent-reported depressive symptoms were assessed at pretest and post intervention, as well as 6- and 12-months follow-up. Clinical assessment of depression was assessed at pretest and 6-months follow-up.

resultsIntent-to-treat analyses revealed that the decrease in adolescent-rated depressive symptoms was significantly larger in the intervention condition than in the control condition. There was no significant difference in decrease of parent-rated depressive symptoms between both conditions.

conclusionsBased on the findings, we recommend the implementation of screening and prevention in schools, according the basics of this study design. Since this is a new step forward, we discuss the clinical impact and challenges, as well possibilities for future research.

trial registrationThe study is registered in the Dutch Trial Register for RCT's ( NTR5725 ). Date registered: 11 March 2016.

Indexed as

AdolescentChildCognitive Behavioral TherapyDepressionFemaleHumansMaleAdolescenceCognitive behavioral therapyDepressionPreventionSchool

Identifiers

PMID32703288
PMCPMC7379355

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.