ArticleBMC genomics2020
Breeding history and candidate genes responsible for black skin of Xichuan black-bone chicken.
Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Intestinal Microbiota Structure of Xichuan Black-Bone Chickens and Preliminary Evaluation of a Probiotic-Based Fecal Microbiota Substitute.Microorganisms · 2026Article
- Whole-genome sequencing identifies genetic diversity and adaptive signatures of hypoxia and ultraviolet radiation in Chinese chickens.Journal of advanced research · 2026Article
- Melanin Deposition and Screening of Melanogenesis-Related Differential RNAs and Construction of ceRNA Regulatory Network in Liancheng White Ducks.Animals : an open access journal from MDPI · 2026Article
- Identification of key candidate genes and marker metabolites of melanin synthesis in black-bone chicken.BMC genomics · 2025Article
- Genetic traceability, conservation effectiveness, and selection signatures analysis based on ancestral information: a case study of Beijing-You chicken.BMC genomics · 2025Article
- Article
- Population genomic analysis identifies the complex structural variation at the fibromelanosis (FM) locus in chicken.Scientific reports · 2025Article
- Understanding the skin blackening phenomenon in Youzhou Dark goats based on the histological characteristics of melanocytes.Journal of advanced veterinary and animal research · 2024Article
- Dynamic Transcriptome Profile Analysis of Mechanisms Related to Melanin Deposition in Chicken Muscle Development.Animals : an open access journal from MDPI · 2024Article
- Whole-genome resequencing reveals melanin deposition candidate genes of Luning chicken.BMC genomics · 2024Article
- Characterization of the Coding Sequence of theAnimals : an open access journal from MDPI · 2024Article
- Article
- Whole-genome resequencing of native and imported dairy goat identifies genes associated with productivity and immunity.Frontiers in veterinary science · 2024Article
- Article
- Review
- Identification of Runs of Homozygosity Islands and Functional Variants in Wenchang Chicken.Animals : an open access journal from MDPI · 2023Article
- Population Structure and Genetic Diversity Analysis of "Yufen 1" H Line Chickens Using Whole-Genome Resequencing.Life (Basel, Switzerland) · 2023Article
- Genome-Wide Genetic Structure of Henan Indigenous Chicken Breeds.Animals : an open access journal from MDPI · 2023Article
- The swan genome and transcriptome, it is not all black and white.Genome biology · 2023Article
- Decoding the fibromelanosis locus complex chromosomal rearrangement of black-bone chicken: genetic differentiation, selective sweeps and protein-coding changes in Kadaknath chicken.Frontiers in genetics · 2023Article
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16 authors.
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Abstract
backgroundDomesticated chickens have a wide variety of phenotypes, in contrast with their wild progenitors. Unlike other chicken breeds, Xichuan black-bone chickens have blue-shelled eggs, and black meat, beaks, skin, bones, and legs. The breeding history and the economically important traits of this breed have not yet been explored at the genomic level. We therefore used whole genome resequencing to analyze the breeding history of the Xichuan black-bone chickens and to identify genes responsible for its unique phenotype.
resultsPrincipal component and population structure analysis showed that Xichuan black-bone chicken is in a distinct clade apart from eight other breeds. Linkage disequilibrium analysis showed that the selection intensity of Xichuan black-bone chickens is higher than for other chicken breeds. The estimated time of divergence between the Xichuan black-bone chickens and other breeds is 2.89 ka years ago. Fst analysis identified a selective sweep that contains genes related to melanogenesis. This region is probably associated with the black skin of the Xichuan black-bone chickens and may be the product of long-term artificial selection. A combined analysis of genomic and transcriptomic data suggests that the candidate gene related to the black-bone trait, EDN3, might interact with the upstream ncRNA LOC101747896 to generate black skin color during melanogenesis.
conclusionsThese findings help explain the unique genetic and phenotypic characteristics of Xichuan black-bone chickens, and provide basic research data for studying melanin deposition in animals.
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