Evidence map›Paper›PMID 32703056›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2021

High-altitude rodents have abundant collaterals that protect against tissue injury after cerebral, coronary and peripheral artery occlusion.

James E Faber, Jay F Storz, Zachary A Cheviron, Hua Zhang

Open access · hybridAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Genetic determinants of insufficiency of the collateral circulation.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Sanctuary sites in cortical stroke.Frontiers in neurology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Large differences in collateral blood vessel abundance among individuals arise from multiple genetic variants.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  11. Therapeutic Induction of Collateral Flow.Translational stroke research · 2023
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

James E FaberDepartment of Cell Biology and Physiology, University of North Carolina at Chapel Hill,  Chapel Hill,  NC, USA.
Jay F StorzSchool of Biological Sciences, University of Nebraska, Lincoln, NE, USA.
Zachary A ChevironDivision of Biological Sciences, University of Montana, Missoula, MT, USA.
Hua ZhangDepartment of Cell Biology and Physiology, University of North Carolina at Chapel Hill,  Chapel Hill,  NC, USA.ORCID 0000-0003-4625-1916
University of North Carolina at Chapel Hill · USUniversity of Montana · USUniversity of Nebraska–Lincoln · US

Funding

Targeting the Pial Collateral Circulation for Mitigation of Cerebral IschemiaR01NS083633 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ZHANG, HUA · 2013 to 2023
$4.5M
Mutational Pleiotropy, Epistasis, and the Adaptive Evolution of Hemoglobin FunctionR01HL087216 · NHLBI · UNIVERSITY OF NEBRASKA LINCOLN · PI STORZ, JAY · 2008 to 2021
$4.5M
NHLBI NIH HHS R01 HL087216NINDS NIH HHS R01 NS083633
6 · The paper itself

Abstract

Collateral number/density varies widely in brain and other tissues among strains of

Indexed as

AltitudeAdaptation, PhysiologicalAnimalsArterial Occlusive DiseasesCerebral ArteriesCircle of WillisCollateral CirculationCoronary Artery DiseaseFemaleGuinea PigsIschemiaMaleMiceMice, Inbred BALB CMice, Inbred C57BLMyocardial InfarctionCollateral circulationcoronary artery diseasehigh-altitude genetic adaptationperipheral artery diseasestroke

Identifiers

PMID32703056
PMCPMC7983333
OpenAlexW3044435552

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.