Evidence map›Paper›PMID 32703018›Full record

ArticleCirculation. Arrhythmia and electrophysiology2020

Procedural Patterns and Safety of Atrial Fibrillation Ablation: Findings From Get With The Guidelines-Atrial Fibrillation.

Zak Loring, DaJuanicia N Holmes, Roland A Matsouaka, Anne B Curtis, John D Day, Nihar Desai, Kenneth A Ellenbogen, Gregory K Feld, Gregg C Fonarow, David S Frankel and 8 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Circulation. Arrhythmia and electrophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 5 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 5 syntheses or guidelines pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Guideline
  4. Predictors of recurrence after catheter ablation and electrical cardioversion of atrial fibrillation: an umbrella review of meta-analyses.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Pooled it
  5. Pooled it
  6. Observational
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  9. Review
  10. Review
  11. Outcomes of atrial fibrillation ablation in community hospitals with and without onsite cardiothoracic surgery availability.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
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  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 16 institutions in 1 country.

Zak LoringDuke Clinical Research Institute (Z.L., D.N.H., R.A.M., J.P.P.), Duke University Medical Center.
DaJuanicia N HolmesDuke Clinical Research Institute (Z.L., D.N.H., R.A.M., J.P.P.), Duke University Medical Center.
Roland A MatsouakaDuke Clinical Research Institute (Z.L., D.N.H., R.A.M., J.P.P.), Duke University Medical Center.
Anne B CurtisDepartment of Medicine, University at Buffalo, NY (A.B.C.).
John D DayIntermountain Medical Center Heart Institute, Intermountain Medical Center, Murray, UT (J.D.D.).
Nihar DesaiCardiovascular Medicine Section, Yale University, New Haven, CT (N.D.).
Kenneth A EllenbogenDivision of Cardiology, Virginia Commonwealth University, Richmond (K.A.E.).
Gregory K FeldDepartment of Medicine, University of California San Diego (G.K.F.).
Gregg C FonarowDepartment of Medicine, University of California Los Angeles (G.C.F.).
David S FrankelCardiovascular Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia (D.S.F.).
Jodie L HurwitzNorth Texas Heart Center, Dallas (J.L.H.).
Bradley P KnightFeinberg School of Medicine, Northwestern University, Chicago, IL (B.P.K.).
Jose A JoglarDepartment of Cardiology, University of Texas, Southwestern Medical Center, Dallas (J.A.J.).
Andrea M RussoCooper Medical School of Rowan University, Camden, NJ (A.M.R.).
Mandeep S SidhuDivision of Cardiology, Albany Medical Center, NY (M.S.S.).
Mintu P TurakhiaVA Palo Alto Health Care System, Palo Alto, CA (M.P.T.).
William R LewisMetroHealth System Campus, Case Western Reserve University, Cleveland, OH (W.R.L.).
Jonathan P PicciniDuke Clinical Research Institute (Z.L., D.N.H., R.A.M., J.P.P.), Duke University Medical Center.
Duke Medical Center · USAlbany Medical Center Hospital · USAmerican Heart Association · USCooper Medical School of Rowan University · USDuke University · USIntermountain Medical Center · USMetroHealth Medical Center · USNorthwestern University · USThe University of Texas Southwestern Medical Center · USUniversity at Buffalo, State University of New York · USUniversity of California, Los Angeles · USUniversity of Pennsylvania · USUniversity of San Diego · USVA Palo Alto Health Care System · USVirginia Commonwealth University · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Postdoctoral Training in Cardiovascular Clinical ResearchT32HL069749 · NHLBI · DUKE UNIVERSITY · PI MARK, DANIEL B · 2003 to 2023
$6.7M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS T32 HL069749
6 · The paper itself

Abstract

backgroundCatheter ablation is an increasingly used treatment for symptomatic atrial fibrillation (AF). However, there are limited prospective, nationwide data on patient selection and procedural characteristics. This study describes patient characteristics, techniques, treatment patterns, and safety outcomes of patients undergoing AF ablation.

methodsA total of 3139 patients undergoing AF ablation between 2016 and 2018 in the Get With The Guidelines-Atrial Fibrillation registry from 24 US centers were included. Patient demographics, medical history, procedural details, and complications were abstracted. Differences between paroxysmal and patients with persistent AF were compared using Pearson χ

resultsPatients undergoing AF ablation were predominantly male (63.9%) and White (93.2%) with a median age of 65. Hypertension was the most common comorbidity (67.6%), and patients with persistent AF had more comorbidities than patients with paroxysmal AF. Drug refractory, paroxysmal AF was the most common ablation indication (class I, 53.6%) followed by drug refractory, persistent AF (class I, 41.8%). Radiofrequency ablation with contact force sensing was the most common ablation modality (70.5%); 23.7% of patients underwent cryoballoon ablation. Pulmonary vein isolation was performed in 94.6% of de novo ablations; the most common adjunctive lesions included left atrial roof or posterior/inferior lines, and cavotricuspid isthmus ablation. Complications were uncommon (5.1%) and were life-threatening in 0.7% of cases.

conclusionsMore than 98% of AF ablations among participating sites are performed for class I or class IIA indications. Contact force-guided radiofrequency ablation is the dominant technique and pulmonary vein isolation the principal lesion set. In-hospital complications are uncommon and rarely life-threatening.

Indexed as

AgedAtrial FibrillationCatheter AblationCryosurgeryFemaleGuideline AdherenceHumansMaleMiddle AgedPostoperative ComplicationsPractice Guidelines as TopicPractice Patterns, Physicians'Pulmonary VeinsRegistriesTime FactorsTreatment Outcomeatrial fibrillationcatheter ablationguideline adherencehypertensionpulmonary vein

Identifiers

PMID32703018
PMCPMC7502261
OpenAlexW3044219145

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.