Observational studyCirculation. Cardiovascular quality and outcomes2020
Multiple Vulnerabilities to Health Disparities and Incident Heart Failure Hospitalization in the REGARDS Study.
Observational study in Circulation. Cardiovascular quality and outcomes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Influence of Social Determinants of Health on Heart Failure Outcomes: A Systematic Review.Journal of the American Heart Association · 2023Pooled it
- Trends and Demographic Disparities Among Adults With Sudden Cardiac Death and Diabetes Mellitus in the United States: A Nationwide Analysis.Journal of arrhythmia · 2026Article
- Large-scale proteomics to identify novel biomarkers linking social determinants of health to heart failure risk.Science advances · 2026Article
- Neighborhood-Level Socially Determined Vulnerabilities and Outcomes After Heart Failure Hospitalization.Journal of the American Heart Association · 2026Article
- Prevalence and Incidence of Heart Failure Phenotypes Among Transgender and Gender-Diverse Adults in the United States.Journal of the American Heart Association · 2026Article
- Socioeconomic Disadvantage, John Henryism, and Incident Heart Failure in the Jackson Heart Study.Circulation. Population health and outcomes · 2026Article
- A metabolite index of ultra-processed food intake is associated with stroke, cancer mortality, and all-cause mortality.medRxiv : the preprint server for health sciences · 2026Article
- SDoH-GPT: using large language models to extract social determinants of health.Journal of the American Medical Informatics Association : JAMIA · 2026Article
- Dietary Inflammatory Score and Incident Heart Failure in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study.Journal of cardiac failure · 2025Article
- Patient-Reported Social Determinants of Health in Patients With Heart Failure.Journal of the American Heart Association · 2025Observational
- Income, education, and the clustering of risk in cardiovascular disease in the US, 1999-2018: an observational study.Lancet regional health. Americas · 2025Article
- Examining Healthy Lifestyles as a Mediator of the Association Between Socially Determined Vulnerabilities and Incident Heart Failure.Circulation. Cardiovascular quality and outcomes · 2025Article
- Article
- The Cumulative Burden of Social Risk Factors and 10-Year Change in Quality of Life.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Importance of medical home domains on emergency visits using a cross-sectional national survey of US children.BMJ open · 2024Article
- Social Determinants of Health and Cardiovascular Risk among Adults with Diabetes: The Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study.Diabetes & metabolism journal · 2024Article
- Evaluating the prognostic value of systemic immune-inflammatory index in patients with acute decompensated heart failure.ESC heart failure · 2024Article
- Heart disease and heart failure: Trends and disparities in mortality rates in the United States from 2000 to 2020.American heart journal plus : cardiology research and practice · 2024Article
- The systemic inflammation response index as a significant predictor of short-term adverse outcomes in acute decompensated heart failure patients: a cohort study from Southern China.Frontiers in endocrinology · 2024Article
- Preventing new-onset heart failure: Intervening at stage A.American journal of preventive cardiology · 2023Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundSocially determined vulnerabilities (SDVs) to health disparities often cluster within the same individual. SDVs are separately associated with increased risk of heart failure (HF). The objective of this study was to determine the cumulative effect of SDVs to health disparities on incident HF hospitalization. METHODS AND
resultsUsing the REGARDS (Reasons for Geographic and Racial Differences in Stroke) cohort study, we studied 25 790 participants without known HF and followed them for 10+ years. Our primary outcome was an incident HF hospitalization through December 31, 2016. Guided by the Healthy People 2020 framework for social determinants of health, we examined 10 potential SDVs. We retained SDVs associated with incident HF hospitalization (
conclusionsA greater number of SDVs significantly increased risk of incident HF hospitalization among adults <65 years, which persisted after adjustment for cardiovascular risk factors. Using a simple SDV count that could be obtained from a social history during clinical assessment may identify younger individuals at increased risk.
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