SynthesisMedicine2020
Risk factors for venous thromboembolism following spinal surgery: A meta-analysis.
Synthesis in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07713875 (Extended Prophylactic Anticoagulation Following Spinal Surgery for Metastatic Disease), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Extended Prophylactic Anticoagulation Following Spinal Surgery for Metastatic Disease
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Risk Factors for Venous Thrombosis after Spinal Surgery: A Systematic Review and Meta-analysis.Computational and mathematical methods in medicine · 2022Pooled it
- Analysis of risk factors for deep vein thrombosis after lumbar endoscopic single-segment decompression without fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Thoracolumbar spine surgery in the post-pandemic era: a national retrospective analysis of thrombotic complications, vaccination status, and prior hospitalization with COVID-19.Asian spine journal · 2026Article
- Risk factors for deep vein thrombosis and pulmonary embolism in patients undergoing spinal fusion for adult spinal deformity.Spine deformity · 2026Article
- Venous Thromboembolism in Spinal Fusion Surgery: A Literature Review of Economic Impact, Risk Factors, and Preoperative Management.Spine surgery and related research · 2025Review
- Analysis of risk factors and establishment of prediction model for lower extremity deep vein thrombosis after lumbar fusion surgery.BMC surgery · 2024Article
- Frequency and Associated Factors of Venous Thromboembolism in Cervical Spine Surgery.International journal of spine surgery · 2024Article
- Venous Thromboembolism Rates Have Not Decreased in Elective Lumbar Fusion Surgery from 2011 to 2020.Global spine journal · 2024Article
- Development of a Predictive Nomogram Model for Early Deep Vein Thrombosis in Postoperative Spontaneous Intracerebral Hemorrhage Patients.International journal of general medicine · 2024Article
- Construction of nomogram model for risk of venous thromboembolism after spine surgery based on thromboelastography and coagulation indices.Frontiers in medicine · 2024Article
- Nomogram for predicting postoperative deep vein thrombosis in patients with spinal fractures caused by high-energy injuries.Archives of orthopaedic and trauma surgery · 2024Article
- Risk factors for postoperative DVT exacerbation or new DVT in patients with spinal cord injury complicated with cervical fracture.Frontiers in cardiovascular medicine · 2024Article
- Using Predictive Modeling and Supervised Machine Learning to Identify Patients at Risk for Venous Thromboembolism Following Posterior Lumbar Fusion.Global spine journal · 2023Article
- The Risk of Venous Thromboembolism after Thoracolumbar Spine Surgery: A Population-Based Cohort Study.Journal of clinical medicine · 2023Article
- Using the cobweb classification system as a digital location system for the neurologic compression in cervical degenerative disease.JOR spine · 2021Article
- D-Dimer Levels Are Not Elevated in SARS-CoV-2 IgG Positive Patients Undergoing Elective Orthopedic Surgery.Journal of clinical medicine · 2021Article
- The influence of modifiable risk factors on short-term postoperative outcomes following cervical spine surgery: A retrospective propensity score matched analysis.EClinicalMedicine · 2021Article
- Antithrombotic Therapy in Spinal Surgery Does Not Impact Patient Safety-A Single Center Cohort Study.Frontiers in surgery · 2021Article
- The Impact of D-Dimer on Postoperative Deep Vein Thrombosis in Patients with Thoracolumbar Fracture Caused by High-Energy Injuries.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
- Using machine learning and big data for the prediction of venous thromboembolic events after spine surgery: A single-center retrospective analysis of multiple models on a cohort of 6869 patients.Journal of craniovertebral junction & spineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the risk factors for postoperative venous thromboembolism (VTE) in patients undergoing spinal surgery.
methodsLiterature published in PubMed, Embase, the Cochrane Library, and Web of Science was systematically reviewed to assess risk factors for VTE following spinal surgery. The data analysis was conducted with STATA 12.0. Data were pooled using fixed-effects or random-effects models according to the heterogeneity among the included studies.
resultsTwenty-six studies involving 3,216,187 patients were included in this meta-analysis, and the total incidence of VTE after spinal surgery was 0.35% (0.15-29.38%). The pooled analysis suggested that the incidence of VTE after spinal surgery was higher in such aspects as increasing age (weighted mean difference [WMD] 0.55 years, 95% confidence interval [CI] 0.33-0.78, P < .001), female sex (odds ratio [OR] 1.12, 95% CI 1.01-1.25; P = .034), diabetes (OR 1.34, 95% CI 1.29-1.44; P < .001), chronic kidney disease (OR = 8.31, 95% CI 1.98-34.93; P = .004), nonambulatory preoperative activity status (OR 3.67, 95% CI 2.75-4.83; P < .001), D-dimer level (WMD 1.023, 95% CI 0.162-1.884; P = .02), long duration of operation (WMD 0.73, 95% CI 0.21-1.24; P = .006), spine fusion (OR 1.54, 95% CI 1.31-1.82; P < .001), and blood transfusion (OR 2.31, 95% CI 1.73-3.07; P < .001), and the differences were statistically significant. However, there were no significant differences in body mass index, obesity, hypertension, coronary heart disease, spondylolisthesis, intraoperative blood loss, surgical procedures (anterior lumbar interbody fusion vs posterior intervertebral fusion /translaminar lumbar interbody fusion), or surgical site (lumbar vs thoracic) (all P > .05).
conclusionBased on our meta-analysis, we identified several important factors that increased the risk of VTE after spinal surgery. We hope our study provides assistance to spine surgeons so that they can adequately analyze and assess risk factors in patients and then develop preventive measures to reduce the incidence of VTE.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.