Evidence map›Paper›PMID 32702817›Full record

ArticleMedicine2020

A comprehensive evaluation of single nucleotide polymorphisms associated with atrophic gastritis risk: A protocol for systematic review and network meta-analysis.

Zhen-Yu Tang, Zhuo-Miao Ye, Jing-Hui Zheng, Feng Jiang, You-Ming Tang

Abstract read
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhen-Yu TangGuangxi University of Chinese Medicine.
Zhuo-Miao YeRuikang School of Clinical Medicine, Guangxi University of Chinese Medicine.
Jing-Hui ZhengDepartment of Cardiology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine.
Feng JiangDepartment of Cardiology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine.
You-Ming TangDepartment of Cardiology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine.ORCID 0000-0002-5649-2273

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSingle nucleotide polymorphisms (SNPs) have been inconsistently associated with atrophic gastritis (AG) risk. This meta-analysis aimed to synthesize relevant data on SNPs associated with AG.

methodsTo identify all associated studies of SNPs and AG published, databases had been searched through January 2020 from the databases of PubMed, China National Knowledge Infrastructure (CNKI), Web of Science, Embase, the Chinese Science and Technology Periodical Database (VIP), Cochrane Library, and Wanfang databases. With the help of network meta-analysis and Thakkinstian algorithm, the best genetic model with the strongest correlation with AG was selected, the final result - matching to the noteworthy correlation - was obtained by referring to the false positive reporting rate (false positive report probability, FPRP). Based on STREGA's stated criteria, the methodological quality of the data we collected was valued. Both Stata 14.0 and GeMTC will be used for a comprehensive review of the system and will be used in our meta-analysis.

resultsThis study will provide a high-quality evidence to find the SNP most associated with AG susceptibility and the best genetic model.

conclusionsThis study will explore which SNP is most associated with AG susceptibility. REGISTRATION: INPLASY202050016.

Indexed as

Gastritis, AtrophicGenetic Predisposition to DiseasePolymorphism, Single NucleotideAlgorithmsChinaFemaleHumansMaleNetwork Meta-Analysis as TopicSystematic Reviews as Topic

Identifiers

PMID32702817
PMCPMC7373582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.