ArticleNeuroImage2020
Lasting consequences of concussion on the aging brain: Findings from the Baltimore Longitudinal Study of Aging.
Article in NeuroImage, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Investigating the relationship between mild traumatic brain injury and Alzheimer's disease and related dementias: a systematic review.Journal of neurology · 2022Pooled it
- Systematic Review of the Long-Term Neuroimaging Correlates of Mild Traumatic Brain Injury and Repetitive Head Injuries.Frontiers in neurology · 2021Pooled it
- The second decade of DTI in TBI part 1: a systematic review of mild TBI.Frontiers in neurologyPooled it
- A Novel Video-Based Method to Estimate American Football Helmet Pad Deformation During Impact Testing.Annals of biomedical engineering · 2026Article
- The Relationship of Prior Concussion and Contact Sport Exposure With Cortical Macro and Microstructure.Human brain mapping · 2025Article
- Investigating the Association of Concussion and Contact Sport Exposure History With Brain Microstructure Using Quantitative Susceptibility Mapping.Human brain mapping · 2025Article
- Structural Magnetic Resonance Imaging Brain Age Investigation in Athletes with Persistent Postconcussion Syndrome.Neurotrauma reports · 2025Article
- Brain morphometry in former American football players: findings from the DIAGNOSE CTE research project.Brain : a journal of neurology · 2024Article
- 18F-Flortaucipir (AV1451) imaging identifies grey matter atrophy in retired athletes.Journal of neurology · 2024Article
- Maintaining Cognitive Performance at the Expense of Gait Speed for Asymptomatic Concussed Athletes: A Novel Dual-Task and Post-Exercise Assessment.Brain sciences · 2024Article
- Associations of prior concussion severity with brain microstructure using mean apparent propagator magnetic resonance imaging.Human brain mapping · 2024Article
- Prospective Study of Gray Matter Atrophy Following Pediatric Mild Traumatic Brain Injury.Neurology · 2023Article
- A review of brain regions and associated post-concussion symptoms.Frontiers in neurology · 2023Review
- Association of liver disease with brain volume loss, cognitive decline, and plasma neurodegenerative disease biomarkers.Neurobiology of aging · 2022Article
- The Pupillary Light Reflex as a Biomarker of Concussion.Life (Basel, Switzerland) · 2021Article
- Structural brain differences in professional Australian rules footballers following mild traumatic brain injury: When head size matters.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Studies suggest that concussions may be related to increased risk of neurodegenerative diseases, such as Chronic Traumatic Encephalopathy and Alzheimer's Disease. Most neuroimaging studies show effects of concussions in frontal and temporal lobes of the brain, yet the long-term impacts of concussions on the aging brain have not been well studied. We examined neuroimaging data from 51 participants (mean age at first imaging visit=65.1 ± 11.23) in the Baltimore Longitudinal Study of Aging (BLSA) who reported a concussion in their medical history an average of 23 years prior to the first imaging visit, and compared them to 150 participants (mean age at first imaging visit=66.6 ± 10.97) with no history of concussion. Participants underwent serial structural MRI over a mean of 5.17±6.14 years and DTI over a mean of 2.92±2.22 years to measure brain structure, as well as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.