Evidence map›Paper›PMID 32702203›Full record

ArticleArthritis care & research2021

Impact of Psychiatric Comorbidity on Health Care Use in Rheumatoid Arthritis: A Population-Based Study.

Carol A Hitchon, Randy Walld, Christine A Peschken, Charles N Bernstein, James M Bolton, Renée El-Gabalawy, John D Fisk, Alan Katz, Lisa M Lix, James Marriott and 4 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Arthritis care & research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Research progress on rheumatoid arthritis-associated depression.Frontiers in behavioral neuroscience · 2022
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Carol A HitchonUniversity of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0001-5547-3268
Randy WalldUniversity of Manitoba, Winnipeg, Manitoba, Canada.
Christine A PeschkenUniversity of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0002-4269-5213
Charles N BernsteinUniversity of Manitoba, Winnipeg, Manitoba, Canada.
James M BoltonUniversity of Manitoba, Winnipeg, Manitoba, Canada.
Renée El-GabalawyUniversity of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0002-3445-5607
John D FiskNova Scotia Health Authority and Dalhousie University, Halifax, Nova Scotia, Canada.
Alan KatzUniversity of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0001-8280-7024
Lisa M LixUniversity of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0001-8685-3212
James MarriottUniversity of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0001-5491-0569
Scott B PattenUniversity of Calgary, Calgary, Alberta, Canada.ORCID 0000-0001-9871-4041
Jitender SareenUniversity of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0001-8573-6495
Alexander SingerUniversity of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0001-5436-8394
Ruth Ann MarrieUniversity of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0002-1855-5595
University of Manitoba · CADalhousie University · CAUniversity of Calgary · CA

Funding

CIHR THC-135234
6 · The paper itself

Abstract

objectivePsychiatric comorbidity is frequent in rheumatoid arthritis (RA) and complicates treatment. The present study was undertaken to describe the impact of psychiatric comorbidity on health care use (utilization) in RA.

methodsWe accessed administrative health data (1984-2016) and identified a prevalent cohort with diagnosed RA. Cases of RA (n = 12,984) were matched for age, sex, and region of residence with 5 controls (CNT) per case (n = 64,510). Within each cohort, we identified psychiatric morbidities (depression, anxiety, bipolar disorder, and schizophrenia [PSYC]), with active PSYC defined as ≥2 visits per year. For the years 2006-2016, annual rates of ambulatory care visits (mean ± SD per person) categorized by provider (family physician [FP], rheumatologist, psychiatrist, other specialist), hospitalization (% of cohort), days of hospitalization (mean ± SD), and dispensed drug types (mean ± SD per person) were compared among 4 groups (CNT, CNT plus PSYC, RA, and RA plus PSYC) using generalized linear models adjusted for age, sex, rural versus urban residence, income quintile, and total comorbidities. Estimated rates are reported with 95% confidence intervals (95% CIs). We tested within-person and RA-PSYC interaction effects.

resultsSubjects with RA were mainly female (72%) and urban residents (59%), with a mean ± SD age of 54 ± 16 years. Compared to RA without PSYC, RA with PSYC had more than additive (synergistic) visits (standardized mean difference [SMD] 10.92 [95% CI 10.25, 11.58]), hospitalizations (SMD 13% [95% CI 0.11, 0.14]), and hospital days (SMD 3.63 [95% CI 3.06, 4.19]) and were dispensed 6.85 more medication types (95% CI 6.43, 7.27). Cases of RA plus PSYC had increased visits to FPs (an additional SMD 8.92 [95% CI 8.35, 9.46] visits). PSYC increased utilization in within-person models.

conclusionManaging psychiatric comorbidity effectively may reduce utilization in RA.

Indexed as

AdultAgedArthritis, RheumatoidComorbidityDatabases, FactualFemaleHealth ResourcesHospitalizationHumansMaleManitobaMental DisordersMental HealthMiddle AgedOffice VisitsPolypharmacyPrescription Drugs

Identifiers

PMID32702203
PMCPMC7839671
OpenAlexW3045099581

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.