ArticlePloS one2020
Rate of opioid use disorder in adults who received prescription opioid pain therapy-A secondary data analysis.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 10 citations in OpenAlex.
- Development and feasibility of a sex- and gender-sensitive primary care intervention for patients with chronic non-cancer pain receiving long-term opioid therapy (GESCO): a study protocol.Pilot and feasibility studies · 2024Article
- Opioid Use Disorder: A Qualitative Exploratory Analysis of Potential Misunderstandings in Patients with Chronic Non-Cancer Pain.Journal of pain research · 2024Article
- [Dealing with "complex" pain patients in eye surgery : Perioperative management of patients with pre-existing chronic pain, opioid consumption and opioid use disorder].Die Ophthalmologie · 2023Review
- Risk factors for opioid use disorder after severe burns in adults.American journal of surgery · 2023Article
- Patient-centered quality measurement for opioid use disorder: Development of a taxonomy to address gaps in research and practice.Substance abuse · 2022Review
- [Critical discussion of new data regarding prevalence of opioid use disorder in patients with chronic pain in Germany].Schmerz (Berlin, Germany) · 2022Review
- Novel Synthetic Opioids (NSO) Use in Opioid Dependents Entering Detoxification Treatment.Frontiers in psychiatry · 2022Article
- Subtypes in Patients Taking Prescribed Opioid Analgesics and Their Characteristics: A Latent Class Analysis.Frontiers in psychiatry · 2022Article
- Abuse of Non-opioid Analgesics in Germany: Prevalence and Associations Among Self-Medicated Users.Frontiers in psychiatry · 2022Article
- Correction: Rate of opioid use disorder in adults who received prescription opioid pain therapy-A secondary data analysis.PloS one · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsData on rates of prescription opioid use disorder (pOUD) in European countries is limited. The aim of this investigation was to analyze a representative population sample regarding the 1-year prevalence of opioid use disorder in patients who received prescription opioid pain therapy and to identify related risk factors.
designCross-sectional secondary data analysis.
settingSecondary data analysis based on data from the 2015 Epidemiological Survey of Substance Abuse (ESA 2015) in Germany.
participantsGerman-speaking individuals living in private households aged 18 to 64 years were investigated. A total of 9204 individuals participated in the survey, resulting in a response rate of 52.2%. PRIMARY AND SECONDARY OUTCOME MEASURES: Primary outcome measure was the weighted prevalence of pOUD in the subgroup of study participants who had received prescription opioids. Secondary outcome measure was an analysis of risk factors connected with pOUD in the same subgroup.
findingsA total of n = 9204 participants were included in the study of which n = 275 had received an opioid prescription in the last 12 months of which n = 54 were diagnosed with pOUD. The weighted 1-year prevalence of pOUD was 21.2% (mild: 14.7% | moderate: 3.5% | severe: 2.9%). Participants who had received opioid pain therapy had significantly higher odds of pOUD if they reported signs of depression (OR: 2.69; CI 95%: 1.13-6.38), inexplicable physical complaints (OR: 2.68; CI 95%: 1.14-6.31) or a psychiatric diagnosis (OR: 4.12; CI 95%: 1.36-12.43), and significantly lower odds of pOUD if they reported the use of non-opioid painkillers (OR: 0.27; CI 95%: 0.09-0.81).
conclusionspOUD is a common phenomenon in working-age patients who receive prescription opioid pain therapy in Germany and may be related to the co-existence of psychosomatic and psychiatric disorders such as depression.
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