Evidence map›Paper›PMID 32701927›Full record

ArticleMedicina oral, patologia oral y cirugia bucal2020

Bacteria associated with periodontal disease are also increased in health.

J López-Martínez, N Chueca, M Padial-Molina, J-A Fernandez-Caballero, F García, F O'Valle, P Galindo-Moreno

Abstract read
In one paragraph

Article in Medicina oral, patologia oral y cirugia bucal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Adjunctive use of3 Biotech · 2025
    Article
  6. Correlation between Inflammasomes and Microbiota in Peri-Implantitis.International journal of molecular sciences · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. The Treatment Efficiency and Microbiota Analysis ofInternational journal of molecular sciences · 2022
    Article
  12. Article
  13. Frontiers in oral health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

J López-MartínezFacultad de Odontología Colegio Máximo, Campus de Cartuja 18071, Granada, Spain pgalindo@ugr.es.
N Chueca
M Padial-Molina
J-A Fernandez-Caballero
F García
F O'Valle
P Galindo-Moreno

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective of this cross-sectional clinical study was to analyze the differences in the microbiome in gingival sulci of adult patients in the presence or absence of chronic periodontitis. MATERIAL AND

methodsPatients with or without periodontal disease were included in this cross-sectional study. Subgingival biofilm samples were collected and analyzed by 16S massive pyrosequencing. Functional analyses were also performed.

resultsA total of 15 phyla, 154 genera and 351 species were detected globally. Differences between disease and non-disease samples were observed in all taxonomical levels which suggest functional profile changes in the community. It was found that the main species associated with non-disease samples were reduced in disease but not completely suppressed. Analysis of the functional potential of the biofilms revealed a significantly higher activity related to endocytosis and phosphatidylinositol signaling in the disease group but lower cell adhesion molecules.

conclusionsSpecific differences between health and disease suggest functional profile changes in the community, although bacteria associated with periodontal disease are also increased in health. Transcriptome studies should be conducted to confirm and deepen metabolic dysfunctions.

Indexed as

Chronic PeriodontitisMicrobiotaAdultBacteriaBiofilmsCross-Sectional StudiesGingivaHumans

Identifiers

PMID32701927
PMCPMC7648922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.