ArticleActa bio-medica : Atenei Parmensis2020
Virological surveillance of SARS-CoV-2 in an Italian northern area: comparison of Real Time RT PCR cycle threshold (Ct) values in three epidemic periods.
Article in Acta bio-medica : Atenei Parmensis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Cycle Threshold Values as Indication of Increasing SARS-CoV-2 New Variants, England, 2020-2022.Emerging infectious diseases · 2023Article
- Elucidation of correlation between SARS-CoV-2 RdRp and N gene cycle threshold (Ct) by RT-PCR with age and gender.Clinica chimica acta; international journal of clinical chemistry · 2022Article
- Socio-demographical Profile of 7285 SARS-Cov-2 Positive Early Cases; Comparison with National Four Epidemic Waves.Medical journal of the Islamic Republic of Iran · 2022Article
- COVID-19 pandemic: Impact on gestational diabetes mellitus prevalence.Diabetes research and clinical practice · 2022Article
- High Viral Load in Upper Respiratory Specimens of Persons With SARS-CoV-2 Infection in a Northern Italian Area.Infectious diseases in clinical practice (Baltimore, Md.) · 2021Article
- Virological surveillance of SARS-CoV-2 in an Italian Northern area: differences in gender, age and Real Time RT PCR cycle threshold (Ct) values in three epidemic periods.Acta bio-medica : Atenei Parmensis · 2021Article
- Epidemiological Significance of SARS-CoV-2 RNA Dynamic in Naso-Pharyngeal Swabs.Microorganisms · 2021Article
- Analysis of the time evolution of COVID-19 lethality during the first epidemic wave in Italy.Acta bio-medica : Atenei Parmensis · 2021Article
- Infection sustained by lineage B.1.1.7 of SARS-CoV-2 is characterised by longer persistence and higher viral RNA loads in nasopharyngeal swabs.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021Article
- Trends of COVID-19 Admissions in an Italian Hub during the Pandemic Peak: Large Retrospective Study Focused on Older Subjects.Journal of clinical medicine · 2021Article
- Monitoring COVID-19 Transmission Risks by Quantitative Real-Time PCR Tracing of Droplets in Hospital and Living Environments.mSphere · 2021Article
- Association between RT-PCR Ct values and COVID-19 new daily cases: a multicenter cross-sectional study.Le infezioni in medicina · 2021Article
- SARS-CoV-2/COVID-19 Testing: The Tower of Babel.Acta bio-medica : Atenei Parmensis · 2020Article
- The identity of public health in COVID-19 times.Acta bio-medica : Atenei Parmensis · 2020Article
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13 authors.
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Abstract
Aim of the study was to investigate the differences in Ct values in nasopharingeal swabs collected in three SARS-CoV-2 epidemic periods: first one from February 23 to March 25 (14 days from lockdown started on March 11); the second one from March 26 to May 18 (14 days from the end of strict lockdown on May 4) and the third one from May 19 until June 15. Viral RNA was detected in nasopharyngeal swabs obtained both from inpatients and outpatients. COVID-19 infection was confirmed according to the Ct values for N1 and N2 genes ascertained by Real-Time RT-PCR assay as described by the CDC. We calculated the prevalence of nasopharyngeal swabs tested positive for SARS-CoV-2, the mean and median of the Cts and the percentage of samples equal or below the Ct value of 25 in the 3 periods considered. The average value of Ct increased, going from 24.80 in the first epidemic period to 26.64 in the second period to 28.50 in the third period (p <0.001). The percentage of samples with Ct lower than or equal to 25 also decreased sharply from 54.7% to 20.0%. These findings need to be integrated with epidemiological and clinical data.
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