Evidence map›Paper›PMID 32701811›Full record

ArticleClinical nuclear medicine2020

Incidental Detection of Lung Adenocarcinoma Presenting as an Anterior Mediastinal Mass on 18F-Fluciclovine PET/CT in a Patient With Primary Prostate Cancer.

Olayinka A Abiodun-Ojo, Akinyemi A Akintayo, Gabriel L Sica, Mehrdad Alemozaffar, David M Schuster

Registry-linked trialOpen access · greenAbstract readCase Reports
In one paragraph

Article in Clinical nuclear medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03081884 (Validation of FACBC as an Early Indicator of Sub-clinical Metastatic Disease Among High-risk Prostate Cancer Patients With Presumed Localized Disease), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03081884 phase2completednot on this map

Validation of FACBC as an Early Indicator of Sub-clinical Metastatic Disease Among High-risk Prostate Cancer Patients With Presumed Localized Disease

TypeinterventionalSponsorEmory UniversityRan2017 to 2019Enrolled61ConditionsCancerArmsFACBC PET-CT Imaging
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Olayinka A Abiodun-OjoFrom the Departments of Radiology and Imaging Sciences.
Akinyemi A AkintayoFrom the Departments of Radiology and Imaging Sciences.
Gabriel L Sica
Mehrdad AlemozaffarDepartment of Urology, Emory University School of Medicine, Atlanta, GA.
David M SchusterFrom the Departments of Radiology and Imaging Sciences.
Emory University · US

Funding

Prostate Cancer Biomarker and Imaging Validation Alliance: Emory University, University of Alabama Birmingham, and University of Texas SouthwesternU01CA113913 · NCI · EMORY UNIVERSITY · PI Martin G. Sanda · 2005 to 2026
$16.4M
NCI NIH HHS U01 CA113913
6 · The paper itself

Abstract

F-fluciclovine is a PET radiotracer approved for detection of recurrent prostate cancer, with utility in other malignancies being investigated. We present the case of a 71-year-old man with high-risk primary prostate cancer (Gleason score 9, prostate-specific antigen 34 ng/mL) and newly diagnosed lung adenocarcinoma. As part of a clinical trial (NCT03081884), preoperative F-fluciclovine PET/CT showed localized abnormal uptake in the prostate gland with extracapsular extension. Additionally, an incidental anterior mediastinal mass measuring 2.2 × 1.8 cm demonstrated abnormal radiotracer uptake. Biopsy of the mediastinal mass confirmed invasive lung adenocarcinoma with solid and acinar patterns and high programmed death 1 ligand expression.

Indexed as

Carboxylic AcidsCyclobutanesIncidental FindingsPositron Emission Tomography Computed TomographyAdenocarcinoma of LungAgedBiopsyHumansMaleMediastinumProstatic NeoplasmsCarboxylic AcidsCyclobutanesfluciclovine F-18

Identifiers

PMID32701811
PMCPMC7609453
OpenAlexW3045895363

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.