Evidence map›Paper›PMID 32701584›Full record

ArticleAIDS (London, England)2020

Exploring patterns and predictors of suicidal ideation among pregnant and postpartum women living with HIV in Kilimanjaro, Tanzania.

Brandon A Knettel, Rimel N Mwamba, Linda Minja, David B Goldston, Judith Boshe, Melissa H Watt, KCMC Option B+ study team

Open access · greenAbstract read
In one paragraph

Article in AIDS (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Brandon A KnettelDuke Global Health Institute, Durham, North Carolina, USA.
Rimel N MwambaDuke Global Health Institute, Durham, North Carolina, USA.
Linda MinjaKilimanjaro Clinical Research Institute, Moshi, Tanzania.
David B GoldstonDuke University Medical School, Durham, North Carolina, USA.
Judith BosheKilimanjaro Christian Medical Centre, Moshi, Tanzania.
Melissa H WattDuke Global Health Institute, Durham, North Carolina, USA.
KCMC Option B+ study team
Duke Institute for Health Innovation · USKilimanjaro Christian Medical Centre · TZDuke University · USUniversity of Utah · US

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
Vanderbilt-Emory-Cornell-Duke Global Health Fellowship Consortium-Expanding Diversity for Global Equity (EDGE)D43TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALIYU, MUKTAR HASSAN, HEIMBURGER, DOUGLAS CORBETT · 2017 to 2021
$6.3M
Sociobehavioral Sciences Research to Improve Care for HIV Infection in TanzaniaD43TW009595 · FIC · KILIMANJARO CHRISTIAN MEDICAL CENTRE · PI Blandina Theophil Mmbaga · 2013 to 2026
$4.2M
A stigma reduction intervention at time of entry into antenatal care to improve PMTCT services in TanzaniaR21TW011053 · FIC · UNIVERSITY OF UTAH · PI MMBAGA, BLANDINA THEOPHIL, WATT, MELISSA H · 2018 to 2019
$424k
Postpartum HIV care engagement in the context of Option B+ in TanzaniaR21AI124344 · NIAID · DUKE UNIVERSITY · PI MMBAGA, BLANDINA THEOPHIL, WATT, MELISSA H · 2016 to 2017
$314k
FIC NIH HHS D43 TW009337FIC NIH HHS D43 TW009595FIC NIH HHS R21 TW011053NIAID NIH HHS P30 AI064518NIAID NIH HHS R21 AI124344
6 · The paper itself

Abstract

objectivePregnant and postpartum women living with HIV face disproportionate risk of depression and suicide, particularly in low-income and middle-income countries. This study examined patterns and predictors of suicidal ideation among women living with HIV in antenatal care in Kilimanjaro, Tanzania.

designWe conducted a longitudinal cohort study of 200 pregnant women living with HIV, with surveys conducted during pregnancy and 6 months postpartum.

methodsPregnant women were recruited during HIV and antenatal care visits at nine clinics. A structured questionnaire was verbally administered in Kiswahili by a trained study nurse. We used simple frequencies and t-tests to measure patterns of suicidal ideation and logistic regression to assess factors associated with suicidal ideation.

resultsSuicidal ideation was endorsed by 12.8% of women during pregnancy and decreased significantly to 3.9% by 6 months postpartum. Ideation was not significantly greater among participants newly diagnosed with HIV. In univariable analyses, suicidal ideation was associated with depression, anxiety, HIV stigma, single relationship status, unknown HIV status of the father of the baby, negative attitudes about antiretroviral medication, and low social support. In the multivariable model, women experiencing anxiety and HIV stigma were significantly more likely to endorse suicidal ideation during pregnancy.

conclusionSuicidal ideation and associated feelings of hopelessness are a critical challenge in antenatal care among women living with HIV, with important implications for quality of life, care engagement, and survival. To better support patients, targeted approaches to address anxiety, depression, stigma, and hopelessness must be prioritized, including crisis support for suicide prevention.

Indexed as

Social StigmaSuicidal IdeationAdultChildCross-Sectional StudiesDepressionFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalLongitudinal StudiesMothersPostpartum PeriodPregnancyPregnancy Complications, InfectiousPregnant People

Identifiers

PMID32701584
PMCPMC7416579
OpenAlexW3043865442

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.