ArticleActa ophthalmologica2021
Increase in treatment of retinopathy of prematurity in the Netherlands from 2010 to 2017.
Article in Acta ophthalmologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Management of retinopathy of prematurity in a tertiary referral neonatal intensive care unit: Treatment rates and the impact of outsourcing laser therapy.Acta ophthalmologica · 2026Observational
- Most Up-to-Date Analysis of Epidemiological Data on the Screening Guidelines and Incidence of Retinopathy of Prematurity in Europe-A Literature Review.Journal of clinical medicine · 2023Article
- Nationwide inventory on retinopathy of prematurity screening in the Netherlands.The British journal of ophthalmology · 2023Article
- Nationwide Increase in the Incidence of Retinopathy of Prematurity in the US-A Growing Problem?JAMA ophthalmology · 2023Article
- Optimization of retinopathy of prematurity screening in a tertiary neonatal unit in Northern Greece based on 16-year data.Journal of perinatology : official journal of the California Perinatal Association · 2022Article
- Considerations for future studies on the effect of late phase oxygen strategies on retinopathy of prematurity.Frontiers in pediatrics · 2022Article
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Authors and funding
25 authors.
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Abstract
purposeCompare patients treated for Retinopathy of Prematurity (ROP) in two consecutive periods.
methodsRetrospective inventory of anonymized neonatal and ophthalmological data of all patients treated for ROP from 2010 to 2017 in the Netherlands, subdivided in period (P)1: 1-1-2010 to 31-3-2013 and P2: 1-4-2013 to 31-12-2016. Treatment characteristics, adherence to early treatment for ROP (ETROP) criteria, outcome of treatment and changes in neonatal parameters and policy of care were compared.
resultsOverall 196 infants were included, 57 infants (113 eyes) in P1 and 139 (275 eyes) in P2, indicating a 2.1-fold increase in ROP treatment. No differences were found in mean gestational age (GA) (25.9 ± 1.7 versus 26.0 ± 1.7 weeks, p = 0.711), mean birth weight (791 ± 311 versus 764 ± 204 grams, p = 0.967) and other neonatal risk factors for ROP. In P2, the number of premature infants born <25 weeks increased by factor 1.23 and higher oxygen saturation levels were aimed at in most centres. At treatment decision, 59.6% (P1) versus 83.5% (P2) (p = 0.263) infants were classified as Type 1 ROP (ETROP classification). Infants were treated with laser photocoagulation (98 versus 96%) and intravitreal bevacizumab (2 versus 4%). Retreatment was necessary in 10 versus 21 (p = 0.160). Retinal detachment developed in 6 versus 13 infants (p = 0.791) of which 2 versus 6 bilateral (p = 0.599).
conclusionIn period 2, the number of infants treated according to the ETROP criteria (Type 1) increased, the number of ROP treatments, retinal detachments and retreatments doubled and the absolute number of retinal detachments increased. Neonatal data did not provide a decisive explanation, although changes in neonatal policy were reported.
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