Evidence map›Paper›PMID 32701110›Full record

ReviewChemical Society reviews2020

Scalable biocatalytic C-H oxyfunctionalization reactions.

Suman Chakrabarty, Ye Wang, Jonathan C Perkins, Alison R H Narayan

Abstract readReview
In one paragraph

Review in Chemical Society reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Empowering Precision C-H Functionalization: Advances in Peroxygenase Engineering.Angewandte Chemie (International ed. in English) · 2026
    Review
  2. Toward Sustainability: Intensification of Light-Driven Whole Cell Biocatalysis.Chembiochem : a European journal of chemical biology · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. High-ThroughputACS central science · 2025
    Article
  7. Photoinduced Copper-Catalyzed Enantioselective Allylic C(Journal of the American Chemical Society · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Direct C-H Hydroxylation ofJournal of the American Chemical Society · 2024
    Article
  14. Advanced Electroanalysis for Electrosynthesis.ACS organic & inorganic Au · 2024
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Suman ChakrabartyLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA. arhardin@umich.edu.
Ye Wang
Jonathan C Perkins
Alison R H Narayan

Funding

Undergrad Supplement: Expanding the synthetic utility of natural product biosynthetic enzymesR35GM124880 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Alison Narayan · 2017 to 2026
$4.5M
NIGMS NIH HHS R35 GM124880
6 · The paper itself

Abstract

Catalytic C-H oxyfunctionalization reactions have garnered significant attention in recent years with their ability to streamline synthetic routes toward complex molecules. Consequently, there have been significant strides in the design and development of catalysts that enable diversification through C-H functionalization reactions. Enzymatic C-H oxygenation reactions are often complementary to small molecule based synthetic approaches, providing a powerful tool when deployable on preparative-scale. This review highlights key advances in scalable biocatalytic C-H oxyfunctionalization reactions developed within the past decade.

Indexed as

BiocatalysisCytochrome P-450 Enzyme SystemMolecular StructureOxygenasesSmall Molecule LibrariesCytochrome P-450 Enzyme SystemOxygenasesSmall Molecule Libraries

Identifiers

PMID32701110
PMCPMC8177087

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.