Evidence map›Paper›PMID 32700955›Full record

Trial reportJournal of consulting and clinical psychology2020

A randomized controlled trial of central executive training (CET) versus inhibitory control training (ICT) for ADHD.

Michael J Kofler, Erica L Wells, Leah J Singh, Elia F Soto, Lauren N Irwin, Nicole B Groves, Elizabeth S M Chan, Caroline E Miller, Kijana P Richmond, Christopher Schatschneider and 1 more

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  4. Does training working memory or inhibitory control produce far-transfer improvements in set shifting for children with ADHD? A randomized controlled trial.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2023
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  13. Attention-deficit/hyperactivity disorder.Nature reviews. Disease primers · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Michael J KoflerDepartment of Psychology.ORCID 0000-0002-8604-3647
Erica L WellsDepartment of Psychology.ORCID 0000-0002-8315-5053
Leah J SinghDepartment of Psychology.ORCID 0000-0003-0242-2859
Elia F SotoDepartment of Psychology.ORCID 0000-0002-6672-287X
Lauren N IrwinDepartment of Psychology.
Nicole B GrovesDepartment of Psychology.
Elizabeth S M ChanDepartment of Psychology.
Caroline E MillerDepartment of Psychology.ORCID 0000-0002-3230-248X
Kijana P RichmondDepartment of Psychology.
Christopher SchatschneiderDepartment of Psychology.ORCID 0000-0002-1700-7685
Christopher J LoniganDepartment of Psychology.

Funding

Evaluating the Efficacy of Central Executive Training (CET) for ADHDR01MH115048 · NIMH · FLORIDA STATE UNIVERSITY · PI KOFLER, MICHAEL J · 2018 to 2022
$1.9M
NIH HHSNIMH NIH HHS R01 MH115048
6 · The paper itself

Abstract

objectiveExecutive function deficits are well-established in ADHD. Unfortunately, replicated evidence indicates that executive function training for ADHD has been largely unsuccessful. We hypothesized that this may reflect insufficient targeting, such that extant protocols do not sufficiently and specifically target the neurocognitive systems associated with phenotypic ADHD behaviors/impairments.

methodChildren with ADHD ages 8-12 (M = 10.41, SD = 1.46; 12 girls; 74% Caucasian/Non-Hispanic) were randomized with allocation concealment to either central executive training (CET; n = 25) or newly developed inhibitory control training (ICT; n = 29). Detailed data analytic plans were preregistered.

resultsBoth treatments were feasible/acceptable based on training duration, child-reported ease of use, and parent-reported high satisfaction. CET was superior to ICT for improving its primary intervention targets: phonological and visuospatial working memory (d = 0.70-0.84). CET was also superior to ICT for improving go/no-go (d = 0.84) but not stop-signal inhibition. Mechanisms of change analyses indicated that CET-related working memory improvements produced significant reductions in the primary clinical endpoints (objectively assessed hyperactivity) during working memory and inhibition testing (indirect effects: β ≥ -.11; 95% CIs exclude 0.0). CET was also superior to ICT on 3 of 4 secondary clinical endpoints (blinded teacher-rated ADHD symptoms; d = 0.46-0.70 vs. 0.16-0.42) and 2 of 4 feasibility/acceptability clinical endpoints (parent-reported ADHD symptoms; d = 0.96-1.42 vs. 0.45-0.65). CET-related gains were maintained at 2-4 month follow-up; ICT-related gains were maintained for attention problems but not hyperactivity/impulsivity per parent report.

conclusionsResults support the use of CET for treating executive function deficits and targeting ADHD behavioral symptoms in children with ADHD. Findings for ICT were mixed at best and indicate the need for continued development/study. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Indexed as

Executive FunctionInhibition, PsychologicalOutcome and Process Assessment, Health CareAttention Deficit Disorder with HyperactivityChildCognitive RemediationFemaleHumansMale

Identifiers

PMID32700955
PMCPMC7384295

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.