Evidence map›Paper›PMID 32700815›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2020

Light-Activated Carbon Monoxide Prodrugs Based on Bipyridyl Dicarbonyl Ruthenium(II) Complexes.

Stepan Geri, Tereza Krunclova, Olga Janouskova, Jiri Panek, Martin Hruby, Daniel Hernández-Valdés, Benjamin Probst, Roger A Alberto, Constantin Mamat, Manja Kubeil and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Stepan GeriInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstrasse 400, 01328, Dresden, Germany.
Tereza KrunclovaDepartment of Biological Models, Institute of Macromolecular Chemistry, Heyrovsky Square 2, 16206, Prague, Czech Republic.ORCID http://orcid.org/0000-0002-5232-8214
Olga JanouskovaDepartment of Biological Models, Institute of Macromolecular Chemistry, Heyrovsky Square 2, 16206, Prague, Czech Republic.ORCID http://orcid.org/0000-0002-1365-6274
Jiri PanekSupramolecular Polymer Systems, Institute of Macromolecular Chemistry, Heyrovsky Square 2, 16206, Prague, Czech Republic.
Martin HrubySupramolecular Polymer Systems, Institute of Macromolecular Chemistry, Heyrovsky Square 2, 16206, Prague, Czech Republic.ORCID http://orcid.org/0000-0002-5075-261X
Daniel Hernández-ValdésDepartment of Chemistry, University of Zurich, Winterthurerstr. 190, 8057, Zurich, Switzerland.
Benjamin ProbstDepartment of Chemistry, University of Zurich, Winterthurerstr. 190, 8057, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-8850-9685
Roger A AlbertoDepartment of Chemistry, University of Zurich, Winterthurerstr. 190, 8057, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-5978-3394
Constantin MamatInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstrasse 400, 01328, Dresden, Germany.ORCID http://orcid.org/0000-0003-1906-3186
Manja KubeilInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstrasse 400, 01328, Dresden, Germany.ORCID http://orcid.org/0000-0001-8857-5922
Holger StephanInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstrasse 400, 01328, Dresden, Germany.ORCID http://orcid.org/0000-0002-2972-2803
Czech Academy of Sciences, Institute of Macromolecular Chemistry · CZHelmholtz-Zentrum Dresden-Rossendorf · DEZHAW Zurich University of Applied Sciences · CH

Funding

Czech Science Foundation 19-01438SDeutscher Akademischer Austauschdienst 57448291FP7 People: Marie-Curie Actions 627113
6 · The paper itself

Abstract

Two photoactivatable dicarbonyl ruthenium(II) complexes based on an amide-functionalised bipyridine scaffold (4-position) equipped with an alkyne functionality or a green-fluorescent BODIPY (boron-dipyrromethene) dye have been prepared and used to investigate their light-induced decarbonylation. UV/Vis, FTIR and

Indexed as

2,2'-DipyridylCarbon MonoxideCell Line, TumorHEK293 CellsHumansProdrugsRuthenium2,2'-DipyridylCarbon MonoxideProdrugsRutheniumanti-apoptotic activityanti-proliferativecellular localisationphotoCORMruthenium(II)

Identifiers

PMID32700815
PMCPMC7496190
OpenAlexW3043998263

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.