Evidence map›Paper›PMID 32700663›Full record

ArticleThe American journal of tropical medicine and hygiene2020

Heavy Rainfall Events and Diarrheal Diseases: The Role of Urban-Rural Geography.

Aniruddha Deshpande, Howard H Chang, Karen Levy

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Waterborne diseases and climate change.Nature reviews. Microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aniruddha Deshpande1Department of Epidemiology, Emory University, Atlanta, Georgia.
Howard H Chang2Department of Biostatistics and Bioinformatics, Emory University, Atlanta, Georgia.
Karen Levy3Gangarosa Department of Environmental Health, Emory University, Atlanta, Georgia.

Funding

Gut microbiome, enteric infections and child growth across a rurual urban gradientR01AI137679 · NIAID · UNIVERSITY OF WASHINGTON · PI EISENBERG, JOSEPH N. S., LEVY, KAREN · 2018 to 2023
$5.3M
Impacts of Human Movement on Regional Strain Distribution of Diarrheagenic E.coliK01AI103544 · NIAID · EMORY UNIVERSITY · PI LEVY, KAREN · 2013 to 2017
$655k
NIAID NIH HHS K01 AI103544NIAID NIH HHS R01 AI137679
6 · The paper itself

Abstract

Diarrheal diseases remain a significant contributor to the global burden of disease. Climate change may increase their incidence by altering the epidemiology of waterborne pathogens through changes in rainfall patterns. To assess potential impacts of future changes in rainfall patterns, we analyzed 33,927 cases of diarrhea across all Ministry of Health clinical facilities in Esmeraldas Province, Ecuador, for a 24-month period from 2013 to 2014, using mixed-effects Poisson regression. We assessed the association between the incidence of diarrheal diseases and heavy rainfall events (HREs) and antecedent rainfall conditions. In rural areas, we found no significant associations between HREs and incidence. In urban areas, dry antecedent conditions were associated with higher incidence than wet conditions. In addition, HREs with dry antecedent conditions were associated with elevated incidence by up to 1.35 (incidence rate ratio, 95% CI: 1.14-1.60) times compared with similar conditions without HREs. These patterns may be driven by accumulation of fecal contamination during dry periods, followed by a flushing effect during HREs. This phenomenon is more important in dense urban environments with more impervious surfaces. These findings suggest that projected increases in rainfall variability and HREs may increase diarrhea burden in urban regions, which are rapidly expanding globally.

Indexed as

RainAdolescentAdultAgedChildChild, PreschoolDiarrheaEcuadorFecesFemaleGeographyHumansIncidenceInfantMaleMiddle Aged

Identifiers

PMID32700663
PMCPMC7470540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.