Evidence map›Paper›PMID 32700628›Full record

Observational studyPharmacogenomics2020

Genetic variation in Charcot-Marie-Tooth genes contributes to sensitivity to paclitaxel-induced peripheral neuropathy.

Yongzhen Chen, Fang Fang, Kelley M Kidwell, Kiran Vangipuram, Lauren A Marcath, Christina L Gersch, James M Rae, Daniel F Hayes, Ellen M Lavoie Smith, N Lynn Henry and 2 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Pharmacogenomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Yongzhen ChenCollege of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USA.
Fang FangDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.
Kelley M KidwellDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.
Kiran VangipuramDepartment of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, MI 48109, USA.
Lauren A MarcathDepartment of Pharmacotherapy, Washington State University College of Pharmacy & Pharmaceutical Sciences, Pullman, WA 99164, USA.
Christina L GerschUniversity of Michigan Rogel Cancer Center, Ann Arbor, MI 48109.
James M RaeUniversity of Michigan Rogel Cancer Center, Ann Arbor, MI 48109.
Daniel F HayesUniversity of Michigan Rogel Cancer Center, Ann Arbor, MI 48109.
Ellen M Lavoie SmithDepartment of Health Behavior & Biological Sciences, University of Michigan School of Nursing, Ann Arbor, MI 48109, USA.
N Lynn HenryUniversity of Michigan Rogel Cancer Center, Ann Arbor, MI 48109.
Andreas S BeutlerDepartment of Anesthesiology, Mayo Clinic, Rochester, MN 55902, USA.
Daniel L HertzUniversity of Michigan Rogel Cancer Center, Ann Arbor, MI 48109.ORCID 0000-0003-0501-1035
University of Michigan · USGTx (United States) · USMayo Clinic · USUniversity of Utah · USWashington State University · US

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Eric R. Fearon · 1988 to 2026
$178.2M
Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Michigan Institute for Clinical and Health Research (MCHR)KL2TR000434 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$1.7M
NCATS NIH HHS KL2 TR000434NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1 TR002240NCI NIH HHS P30 CA046592
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAntineoplastic Agents, PhytogenicCharcot-Marie-Tooth DiseaseCohort StudiesFemaleGenetic VariationHumansMaleMiddle AgedPaclitaxelPolyneuropathiesProspective StudiesAntineoplastic Agents, PhytogenicPaclitaxelARHGEF10FZD3paclitaxelperipheral neuropathypharmacogenomics

Identifiers

PMID32700628
PMCPMC7444626
OpenAlexW3044918321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.