Evidence map›Paper›PMID 32700454›Full record

ArticleMicrobiologyOpen2020

Biofilm formation in Acinetobacter baumannii was inhibited by PAβN while it had no association with antibiotic resistance.

Lihua Chen, Haixia Li, Haichu Wen, Binyu Zhao, Yujia Niu, Qianqian Mo, Yong Wu

Open access · goldAbstract read
In one paragraph

Article in MicrobiologyOpen, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Frontiers in cellular and infection microbiology · 2024
    Article
  13. Article
  14. Synergistic Role of Biofilm-Associated Genes and Efflux Pump Genes in Tigecycline Resistance of Acinetobacter baumannii.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Factors mediatingCurrent research in microbial sciences · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lihua ChenDepartment of Laboratory Medicine, Third Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0002-8882-2361
Haixia LiDepartment of Medical Laboratory, Changsha Medical University, Changsha, China.
Haichu WenDepartment of Laboratory Medicine, Xiangya Medical School of Central South University, Changsha, China.
Binyu ZhaoDepartment of Laboratory Medicine, Xiangya Medical School of Central South University, Changsha, China.
Yujia NiuDepartment of Laboratory Medicine, Xiangya Medical School of Central South University, Changsha, China.
Qianqian MoDepartment of Laboratory Medicine, Xiangya Medical School of Central South University, Changsha, China.
Yong WuDepartment of Laboratory Medicine, Third Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0002-3667-8716
Central South University · CNChangsha Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to investigate the relationship between Acinetobacter baumannii biofilm formation and antibiotic resistance. Furthermore, the effects of PAβN, a potential efflux pump inhibitor, on A. baumannii biofilm formation and dispersion were tested, and the gene expression levels of efflux pumps were determined to study the mechanisms. A total of 92 A. baumannii isolates from infected patients were collected and identified by multiplex PCR. The antimicrobial susceptibility of A. baumannii clinical isolates was tested by VITEK 2 COMPACT

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsBacterial ProteinsBiofilmsDipeptidesDrug Resistance, BacterialGene ExpressionGenotypeHumansMembrane Transport ProteinsMicrobial Sensitivity TestsPolymerase Chain ReactionAdeB protein, Acinetobacter baumanniiAnti-Bacterial AgentsBacterial ProteinsDipeptidesMembrane Transport Proteinsphenylalanine arginine beta-naphthylamideAcinetobacter baumanniiantibiotic resistancebiofilmefflux pumpPAβN

Identifiers

PMID32700454
PMCPMC7520992
OpenAlexW3044044014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.