ArticleObesity surgery2020
Bariatric Surgery Impact on Reproductive Hormones, Semen Analysis, and Sperm DNA Fragmentation in Men with Severe Obesity: Prospective Study.
Article in Obesity surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The effect of obesity interventions on male fertility: a systematic review and meta-analysis.Human reproduction update · 2026Pooled it
- Australasian recurrent pregnancy loss clinical management guideline 2024, part II.The Australian & New Zealand journal of obstetrics & gynaecology · 2024Guideline
- Bariatric Surgery Does Not Improve Semen Quality: Evidence from a Meta-analysis.Obesity surgery · 2022Pooled it
- Semaglutide improved sperm morphology in obese men with type 2 diabetes mellitus and functional hypogonadism.Diabetes, obesity & metabolism · 2025Trial
- The influence of different bariatric surgeries on male sex hormones and semen parameters among infertile obese male patients: an observational study.BMC surgery · 2026Observational
- New Insight Into Male Infertility: Deviation From Basic Tenets of Life.Oxidative medicine and cellular longevity · 2026Review
- Treatment Options for Improving The Semen Quality in Obese Men: A Scoping Review.Journal of multidisciplinary healthcare · 2026Review
- Effect of Bariatric Surgery on Male Infertility: An Updated Meta-Analysis and Literature Review.The world journal of men's health · 2025Article
- Approach to the Patient: Low Testosterone Concentrations in Men With Obesity.The Journal of clinical endocrinology and metabolism · 2025Review
- Weight Loss as Therapeutic Option to Restore Fertility in Obese Men: A Meta-Analytic Study.The world journal of men's health · 2025Article
- Review
- A Review of Semen Analysis: Updates From the WHO Sixth Edition Manual and Advances in Male Fertility Assessment.Cureus · 2024Review
- Sperm DNA Fragmentation: causes, evaluation and management in male infertility.JBRA assisted reproduction · 2024Review
- Phase angle at bioelectric impedance analysis is associated with detrimental sperm quality in idiopathic male infertility: a preliminary clinical study.Frontiers in endocrinology · 2024Article
- Analysis of semen parameters, and hormonal changes of FSH, LH, testosterone, and libido following bariatric surgery.Journal of family medicine and primary care · 2023Article
- Long-term effect of sleeve gastrectomy surgery on Hormonal Profile, Semen Parameters and sexual functions of obese infertile men; a prospective observational study.Basic and clinical andrology · 2023Article
- Fertility outcomes following bariatric surgery.World journal of experimental medicine · 2023Article
- Strategies to Increase Testosterone in Men Seeking Fertility.Urology research & practice · 2023Article
- Testosterone Serum Levels Are Related to Sperm DNA Fragmentation Index Reduction after FSH Administration in Males with Idiopathic Infertility.Biomedicines · 2022Article
- Obesity Surgery Improves Hypogonadism and Sexual Function in Men without Effects in Sperm Quality.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeGrowing evidence in the literature suggests that obesity is capable of altering reproductive hormone levels and male fertility. Effects on classic semen parameters and sperm DNA fragmentation (SDF), however, have not been properly established. Additionally, the impact of bariatric surgery (BS) on those parameters is still controversial. MATERIALS AND
methodsIn Phase 1, 42 patients with obesity and 32 fertile controls were submitted to reproductive hormone evaluation, semen analysis, and SDF testing. In Phase 2, patients with obesity were submitted to BS or clinical follow-up and were invited to 6-month revaluation.
resultsPhase 1: Men with obesity have higher levels of estradiol, LH, and FSH and lower levels of total testosterone (TT) when compared with eutrophic fertile men. Additionally, they present worse semen parameters, with reduction in ejaculated volume and sperm concentration, worse sperm motility and morphology, and higher SDF. Phase 2: 32 patients returned to revaluation. Eighteen were submitted to BS (group S) and 14 were not submitted to any specific therapeutic regimen (group NS). In group S, TT more than doubled after surgery (294.5 to 604 ng/dL, p < 0.0001). Worsening of sperm concentration and total ejaculated sperm count were also noticed, and 2 patients became azoospermic after BS. SDF, however, improved after the procedure. No changes in the variables studied were observed in non-operated patients.
conclusionIn this prospective study, we have found that BS results in improvements in reproductive hormone levels and SDF after 6-month follow-up. Sperm concentration, however, reduced after the procedure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.