ArticleNeuroscience bulletin2020
Joint Multi-modal Parcellation of the Human Striatum: Functions and Clinical Relevance.
Article in Neuroscience bulletin, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Estradiol, Emotion Regulation, and the Limbic System: Effects on Gray Matter Volume.Biological psychiatry global open science · 2026Article
- Intrinsic connectivity patterns of striatal subfields predict individual dimensions of psychopathology and are associated with cholinergic and serotonergic neurotransmission in schizophrenia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- NiCLIP: Neuroimaging contrastive language-image pretraining model for predicting text from brain activation images.bioRxiv : the preprint server for biology · 2025Article
- Decreased low-frequency amplitude of the right caudate nucleus in patients with chronic schizophrenia treated with risperidone combined with clozapine.Frontiers in psychiatry · 2025Article
- Imaging the Limbic System in Parkinson's Disease-A Review of Limbic Pathology and Clinical Symptoms.Brain sciences · 2022Review
- Mapping microstructural gradients of the human striatum in normal aging and Parkinson's disease.Science advances · 2022Article
- An MRI method for parcellating the human striatum into matrix and striosome compartments in vivo.NeuroImage · 2022Article
- Uncovering Cortical Units of Processing From Multi-Layered Connectomes.Frontiers in neuroscience · 2022Article
- Striatal topographical organization: Bridging the gap between molecules, connectivity and behavior.European journal of histochemistry : EJH · 2021Review
- Functional parcellation of human and macaque striatum reveals human-specific connectivity in the dorsal caudate.NeuroImage · 2021Article
- Altered Effective Connectivity Measured by Resting-State Functional Magnetic Resonance Imaging in Posterior Parietal-Frontal-Striatum Circuit in Patients With Disorder of Consciousness.Frontiers in neuroscience · 2021Article
- Neurobiological substrates of the positive formal thought disorder in schizophrenia revealed by seed connectome-based predictive modeling.NeuroImage. Clinical · 2021Article
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Authors and funding
17 authors.
Funding
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Abstract
The human striatum is essential for both low- and high-level functions and has been implicated in the pathophysiology of various prevalent disorders, including Parkinson's disease (PD) and schizophrenia (SCZ). It is known to consist of structurally and functionally divergent subdivisions. However, previous parcellations are based on a single neuroimaging modality, leaving the extent of the multi-modal organization of the striatum unknown. Here, we investigated the organization of the striatum across three modalities-resting-state functional connectivity, probabilistic diffusion tractography, and structural covariance-to provide a holistic convergent view of its structure and function. We found convergent clusters in the dorsal, dorsolateral, rostral, ventral, and caudal striatum. Functional characterization revealed the anterior striatum to be mainly associated with cognitive and emotional functions, while the caudal striatum was related to action execution. Interestingly, significant structural atrophy in the rostral and ventral striatum was common to both PD and SCZ, but atrophy in the dorsolateral striatum was specifically attributable to PD. Our study revealed a cross-modal convergent organization of the striatum, representing a fundamental topographical model that can be useful for investigating structural and functional variability in aging and in clinical conditions.
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