ReviewAnnals of intensive care2020
Management and prevention of anemia (acute bleeding excluded) in adult critical care patients.
Review in Annals of intensive care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 62 citations in OpenAlex.
- Early red blood cell transfusion strategy in septic shock among patients with cancer: the TRANSPORT randomized controlled trial.Intensive care medicine · 2026Trial
- Development and Validation of Machine Learning-Based Models to Predict In-Hospital Mortality in Life-Threatening Ventricular Arrhythmias: Retrospective Cohort Study.Journal of medical Internet research · 2023Trial
- Hematologic and Renal Trends in Cats Undergoing Continuous Renal Replacement Therapy: A Retrospective Case Series with Molidustat Use.Veterinary sciences · 2026Article
- Evaluation of Hospital-Acquired Anemia and Contributing Factors in ICU Patients: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Clinical Evaluation of Microneedle Biosensors for Continuous Lactate Monitoring in Critically Ill Patients.ACS sensors · 2026Article
- Anemia of Critical Illness: A Concise Definitive Review in Critical Care.Critical care medicine · 2026Review
- Exploratory Evaluation of Potential CRP and Ferritin Thresholds and Survival in Critically Ill Patients: A Pilot Prospective ICU Study.Journal of clinical medicine · 2025Article
- Development and validation of a predictive nomogram for sepsis-associated severe anemia.The Journal of international medical research · 2025Article
- Dose-response relationship between transfusion and the incidence of infection in critically ill patients: a systematic review and dose-response meta-analysis.Journal of intensive care · 2025Article
- Whole blood exchange ameliorates acute hemolytic anemia by reducing inflammation and oxidative stress in rats.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Red Blood Cell-Related Phenotype-Genotype Correlations in Chronic and Acute Critical Illnesses (Traumatic Brain Injury Cohort and COVID-19 Cohort).International journal of molecular sciences · 2025Article
- Best practices for iatrogenic anaemia prevention in the intensive care unit: Blood-sparing techniques.Nursing in critical care · 2025Review
- Severe bleeding events among critically ill patients with haematological malignancies.Annals of intensive care · 2024Article
- Outcomes of intracranial hemorrhage in critically ill patients with acute leukemia: Results of a retrospective cohort study.Journal of intensive medicine · 2024Article
- Jehovah's Witness Needing Critical Care: A Narrative Review on the Expanding Arsenal.Critical care research and practice · 2024Review
- Anaemia in the first week may be associated with long-term mortality among critically ill patients: propensity score-based analyses.BMC emergency medicine · 2023Article
- Patient Blood Management, Anemia, and Transfusion Optimization Across Surgical Specialties.Anesthesiology clinics · 2023Review
- Relevance of pre-existing anaemia for patients admitted for acute coronary syndrome to an intensive care unit: a retrospective cohort analysis of 7418 patients.European heart journal open · 2022Article
- Week-One Anaemia was Associated with Increased One-Year Mortality in Critically Ill Surgical Patients.International journal of clinical practice · 2022Article
- Iatrogenic anaemia and transfusion thresholds in ICU patients with COVID-19 disease at a tertiary care hospital.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2021Article
Corrections and comments
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Authors and funding
16 authors at 11 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAnemia is very common in critical care patients, on admission (affecting about two-thirds of patients), but also during and after their stay, due to repeated blood loss, the effects of inflammation on erythropoiesis, a decreased red blood cell life span, and haemodilution. Anemia is associated with severity of illness and length of stay.
methodsA committee composed of 16 experts from four scientific societies, SFAR, SRLF, SFTS and SFVTT, evaluated three fields: (1) anemia prevention, (2) transfusion strategies and (3) non-transfusion treatment of anemia. Population, Intervention, Comparison, and Outcome (PICO) questions were reviewed and updated as needed, and evidence profiles were generated. Analysis of the literature and formulation of recommendations were then conducted according to the GRADE
resultsThe SFAR-SRLF guideline panel provided ten statements concerning the management of anemia in adult critical care patients. Acute haemorrhage and chronic anemia were excluded from the scope of these recommendations. After two rounds of discussion and various amendments, a strong consensus was reached for ten recommendations. Three of these recommendations had a high level of evidence (GRADE 1±) and four had a low level of evidence (GRADE 2±). No GRADE recommendation could be provided for two questions in the absence of strong consensus.
conclusionsThe experts reached a substantial consensus for several strong recommendations for optimal patient management. The experts recommended phlebotomy reduction strategies, restrictive red blood cell transfusion and a single-unit transfusion policy, the use of red blood cells regardless of storage time, treatment of anaemic patients with erythropoietin, especially after trauma, in the absence of contraindications and avoidance of iron therapy (except in the context of erythropoietin therapy).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.