Evidence map›Paper›PMID 32699936›Full record

ArticleVirus genes2020

Unusual mono-reassortant of a Wa-like G1P[8] species A rotavirus containing a DS-1-like (genotype 2) NSP4 gene.

Tung Phan, Tomihiko Ide, Satoshi Komoto, Pattara Khamrin, Shoko Okitsu, Koki Taniguchi, Hideaki Kikuta, Niwat Maneekarn, Satoshi Hayakawa, Hiroshi Ushijima

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Article in Virus genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Tung PhanDivision of Clinical Microbiology, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Tomihiko IdeDepartment of Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Satoshi KomotoDepartment of Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Pattara KhamrinDepartment of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Shoko OkitsuDivision of Microbiology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan.
Koki TaniguchiDepartment of Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Hideaki KikutaPediatric Clinic, Touei Hospital, Sapporo, Hokkaido, Japan.
Niwat ManeekarnDepartment of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Satoshi HayakawaDivision of Microbiology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan.
Hiroshi UshijimaDivision of Microbiology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan. ushijima-hiroshi@jcom.home.ne.jp.ORCID http://orcid.org/0000-0003-4378-3861
Nihon University · JPFujita Health University · JPChiang Mai University · THSapporo Toho Hospital · JPUniversity of Pittsburgh Medical Center · US

Funding

Grant-in-Aid for Scientific Research 16H05360Public Foundation of the Vaccination Research Center 2018-38Public Foundation of the Vaccination Research Center 2019-41
6 · The paper itself

Abstract

Species A rotaviruses are a major cause of acute gastroenteritis in infants and young children worldwide. Reassortment is a common phenomenon due to the segmented nature of the rotavirus genome. The complete coding sequences of a species A rotavirus strain isolated from the feces of a child with acute gastroenteritis in Japan in 2018 were determined using an unbiased viral metagenomics approach. The genetic analysis revealed that the rotavirus strain had an unusual genomic constellation (G1-P[8]-I1-R1-C1-M1-A1-N1-T1-E2-H1), suggesting reassortment of a genotype 1 with a genotype 2 rotavirus, from which the NSP4-encoding gene was acquired.

Indexed as

RotavirusAcute DiseaseChild, PreschoolEvolution, MolecularFecesGastroenteritisGenetic VariationGenome, ViralHumansJapanPhylogenyReassortant VirusesRNA, ViralRotavirus InfectionsToxins, BiologicalViral Nonstructural ProteinsNS28 protein, rotavirusRNA, ViralToxins, BiologicalViral Nonstructural ProteinsDiarrheaJapanReassortmentRotavirus

Identifiers

PMID32699936
OpenAlexW3044528960

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.