Evidence map›Paper›PMID 32699748›Full record

ArticleInternational journal of spine surgery2020

Adjacent Segment Pathology After Treatment With Cervical Disc Arthroplasty or Anterior Cervical Discectomy and Fusion, Part 2: Clinical Results at 7-Year Follow-Up.

Pierce D Nunley, Eubulus J Kerr, David A Cavanaugh, Phillip Andrew Utter, Peter G Campbell, Rishi Wadhwa, Kelly A Frank, Kyle E Marshall, Marcus B Stone

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of spine surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. ProDisc-C versus anterior cervical discectomy and fusion for the surgical treatment of symptomatic cervical disc disease: two-year outcomes of Asian prospective randomized controlled multicentre study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Trial
  2. Article
  3. Article
  4. Review
  5. The Role of Cervical Disc Arthroplasty in Elite Athletes.Current reviews in musculoskeletal medicine · 2023
    Review
  6. Article
  7. Observational
  8. Economic Impact of Revision Operations for Adjacent Segment Disease of the Subaxial Cervical Spine.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2022
    Article
  9. [Analysis of infuence factors of anterior bone loss after cervical disc arthroplasty and its effect on effectiveness].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Pierce D NunleySpine Institute of Louisiana, Shreveport, Louisiana.
Eubulus J KerrSpine Institute of Louisiana, Shreveport, Louisiana.
David A CavanaughSpine Institute of Louisiana, Shreveport, Louisiana.
Phillip Andrew UtterSpine Institute of Louisiana, Shreveport, Louisiana.
Peter G CampbellSpine Institute of Louisiana, Shreveport, Louisiana.
Rishi WadhwaSpine Institute of Louisiana, Shreveport, Louisiana.
Kelly A FrankSpine Institute of Louisiana, Shreveport, Louisiana.
Kyle E MarshallSpine Institute of Louisiana, Shreveport, Louisiana.
Marcus B StoneSpine Institute of Louisiana, Shreveport, Louisiana.
Spine Institute of Louisiana · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdjacent segment pathology (ASP) following cervical disc arthroplasty (CDA) or anterior cervical discectomy and fusion (ACDF) is identified by imaging (RASP) or clinical symptoms (CASP). Clinical symptoms of CASP have been broadly defined, but subsequent adjacent-level surgeries are clear indicators of CASP. Current literature remains inconsistent in the incidence and potential predictors of CASP. Here, we will evaluate a robust data set for the incidence of CASP resulting in subsequent surgery, attempt to identify factors that might affect CASP, and analyze the association of CASP with patient-reported outcomes (PROS) and RASP.

methodsData were prospectively collected during a US Food and Drug Administration randomized, multicenter, investigational device exemption trial comparing CDA (Mobi-C, Zimmer Biomet, Westminster, CO) with ACDF. CASP was defined as any adjacent-level subsequent surgical intervention. Post hoc analyses were conducted on the incidence, time to CASP diagnosis, and relationship of CASP with patient demographics. Longitudinal retrospective case-control analysis was used to assess the correlation of CASP to PROs and radiographic adjacent segment pathology (RASP).

resultsKaplan-Meier estimates indicated significantly lower probability of CASP over time for 1-level (

conclusionsPatients treated with CDA have a lower incidence of CASP than do patients treated with ACDF, although the mechanism remains unclear. CASP and RASP remain uncorrelated in this large data set, but other predictive variables such as treatment, age, and number of levels should be further investigated.

Indexed as

adjacent segment pathologyanterior cervical discectomy and fusioncervical disc arthroplasty

Identifiers

PMID32699748
PMCPMC7343266
OpenAlexW3034567556

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.