Evidence map›Paper›PMID 32699615›Full record

ReviewClinical kidney journal2020

Coronavirus disease 2019 in chronic kidney disease.

Luis D'Marco, María Jesús Puchades, María Romero-Parra, Elena Gimenez-Civera, María José Soler, Alberto Ortiz, José Luis Gorriz

Open access · goldAbstract readReview
In one paragraph

Review in Clinical kidney journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 4 pooled it
2.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 4 syntheses or guidelines pooled it, 97 citations in OpenAlex.

  1. The Impact of the COVID-19 Pandemic on Patients With CKD: Systematic Review of Qualitative Studies.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023
    Pooled it
  2. Pooled it
  3. Incidence and Outcomes of COVID-19 in People With CKD: A Systematic Review and Meta-analysis.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Luis D'MarcoNephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, Valencia, Spain.
María Jesús PuchadesNephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, Valencia, Spain.
María Romero-ParraNephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, Valencia, Spain.
Elena Gimenez-CiveraNephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, Valencia, Spain.
María José SolerNephrology Department, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.ORCID 0000-0003-3621-0766
Alberto OrtizIIS-Fundación Jiménez Diaz UAM and School of Medicine, Universidad Autonoma de Madrid, Madrid, Spain.
José Luis GorrizNephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, Valencia, Spain.ORCID 0000-0002-1134-9051
Universitat de València · ESHospital Universitario Fundación Jiménez Díaz · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical spectrum of coronavirus disease 2019 (COVID-19) infection ranges from asymptomatic infection to severe pneumonia with respiratory failure and even death. More severe cases with higher mortality have been reported in older patients and in those with chronic illness such as hypertension, diabetes or cardiovascular diseases. In this regard, patients with chronic kidney disease (CKD) have a higher rate of all-type infections and cardiovascular disease than the general population. A markedly altered immune system and immunosuppressed state may predispose CKD patients to infectious complications. Likewise, they have a state of chronic systemic inflammation that may increase their morbidity and mortality. In this review we discuss the chronic immunologic changes observed in CKD patients, the risk of COVID-19 infections and the clinical implications for and specific COVID-19 therapy in CKD patients. Indeed, the risk for severe COVID-19 is 3-fold higher in CKD than in non-CKD patients; CKD is 12-fold more frequent in intensive care unit than in non-hospitalized COVID-19 patients, and this ratio is higher than for diabetes or cardiovascular disease; and acute COVID-19 mortality is 15-25% for haemodialysis patients even when not developing pneumonia.

Indexed as

cardiovascular diseasechronic kidney diseaseCOVID-19immunitySARS-CoV-2therapy

Identifiers

PMID32699615
PMCPMC7367105
OpenAlexW3045032839

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.