Evidence map›Paper›PMID 32699584›Full record

ArticleWorld journal of gastrointestinal oncology2020

Immune checkpoint inhibitors induced colitis, stay vigilant: A case report.

Suha Abu Khalaf, Abdulmajeed Albarrak, Mohamad Yousef, Veysel Tahan

Open access · diamondAbstract readCase Reports
In one paragraph

Article in World journal of gastrointestinal oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Suha Abu KhalafDepartment of Internal Medicine, University of Missouri, Columbia, MO 65212, United States. abukhalafs@health.missouri.edu.
Abdulmajeed AlbarrakDepartment of Internal Medicine, College of Medicine, Qassim University, Buraydah 81999, Saudi Arabia.
Mohamad YousefDivision of Gastroenterology and Hepatology, University of Missouri, Columbia, MO 65212, United States.
Veysel TahanDivision of Gastroenterology and Hepatology, University of Missouri, Columbia, MO 65212, United States.
University of Missouri · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColitis is one of the immune-related side effects of immunotherapy. Usually, such type of side effect was reported to develop within a few weeks of treatment initiation, our case started within a few days. CASE SUMMARY: We present a case of a 37-year-old gentleman with bright red loose stools, abdominal pain, and tenesmus. A diagnosis of colitis was made based on endoscopic and histologic findings. Treatment was thereafter continued with oral steroids and discontinuation of the immunotherapy medications. Symptoms resolved after starting the treatment and the patient continued to be symptom-free on subsequent follow-up. The unique about this case report is that the patient developed bloody diarrhea within five days of the 1

conclusionImmunotherapy related complications might occur within days from being on immunotherapy; we need more research to open the way for future pathological and clinical research to further understand the pathophysiology behind it.

Indexed as

Case reportColitisHepatitisImmunotherapyIpilimumabMelanoma

Identifiers

PMID32699584
PMCPMC7340999
OpenAlexW3034642515

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.