Evidence map›Paper›PMID 32699547›Full record

ArticleDrugs in context2020

Kawasaki disease in siblings and a review of drug treatment.

Steven King-Fan Loo, Kam Lun Hon, Alexander Kc Leung, Tak Cheung Yung, Man Ching Yam

Open access · goldAbstract readCase Reports
In one paragraph

Article in Drugs in context, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Steven King-Fan LooThe Hong Kong Institute of Integrative Medicine, The Chinese University of Hong Kong.
Kam Lun HonDepartment of Paediatrics & The Hong Kong Institute of Integrative Medicine, The Chinese University of Hong Kong.
Alexander Kc LeungDepartment of Pediatrics, The University of Calgary and The Alberta Children's Hospital, Calgary, Alberta, Canada.
Tak Cheung YungDepartment of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Hong Kong.
Man Ching YamDepartment of Paediatrics, Prince of Wales Hospital, Hong Kong.
Prince of Wales Hospital · CNQueen Mary Hospital · CNUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have managed two anonymized siblings with Kawasaki disease (KD). The occurrence of KD in the elder brother alerted us to the occurrence of incomplete KD in the younger brother. Both siblings were treated with intravenous immunoglobulin and a high dose of dipyridamole with resolution of the coronary artery aneurysm. Dipyridamole was used instead of aspirin because both siblings were glucose-6-phosphate dehydrogenase deficient for which aspirin was contraindicated. To prevent damage to the coronary arteries, treatment should be started as soon as the diagnosis is made. There have been a lot of advances in medical therapy in recent years, which are reviewed together with conventional proven therapy for KD. Early diagnosis and prompt treatment are important to achieve optimal treatment outcome in KD. Family history of KD among siblings enables clinicians for an earlier diagnosis so as to prevent the disease complications particularly in patients with incomplete features.

Indexed as

COVID-19dipyridamoleintravenous immunoglobulinKawasaki diseasesiblings

Identifiers

PMID32699547
PMCPMC7357683
OpenAlexW3039117875

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.