ArticleScientific reports2020
Racial/ethnic and geographic differences in polybrominated diphenyl ether (PBDE) levels across maternal, placental, and fetal tissues during mid-gestation.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- High-resolution metabolomics of maternal polybrominated diphenyl ethers (PBDE) exposure and preterm birth in the Atlanta African American Maternal-Child Cohort.Communications medicine · 2026Article
- Stressful life events and hypertensive disorders of pregnancy: The role of maternal and fetal inflammation.Pregnancy hypertension · 2026Article
- Gestational PBDE concentrations and functional connectivity in adolescents: The HOME Study.International journal of hygiene and environmental health · 2026Article
- Associations between brominated and organophosphate flame retardant levels and inflammatory biomarkers in maternal blood, cord blood, and placental tissue at mid-gestation.The Science of the total environment · 2025Article
- Psychosocial stress and associations with inflammation in mid-gestation maternal, fetal, and placental tissue.Reproductive toxicology (Elmsford, N.Y.) · 2025Article
- Maternal Thyroid Supplementation Prevents Autistic-relevant Social Behavior and Hypothalamic Oxytocin Depletion Produced by Developmental Exposure to Environmental Toxicants.bioRxiv : the preprint server for biology · 2025Article
- Distribution of polybrominated diphenyl ethers (PBDEs) in placental tissues of maternal and fetal origin in exposed Wistar rats and associations with thyroid hormone levels.Toxicological sciences : an official journal of the Society of Toxicology · 2025Article
- Prenatal exposure to persistent and non-persistent chemical mixtures and associations with adverse birth outcomes in the Atlanta African American Maternal-Child Cohort.Journal of exposure science & environmental epidemiology · 2024Article
- Endocrine disrupting chemical mixture exposure and risk of papillary thyroid cancer in U.S. military personnel: A nested case-control study.The Science of the total environment · 2024Article
- Prenatal exposure to polybrominated diphenyl ether (PBDE) and child neurodevelopment: The role of breastfeeding duration.The Science of the total environment · 2024Article
- Update of the risk assessment of polybrominated diphenyl ethers (PBDEs) in food.EFSA journal. European Food Safety Authority · 2024Article
- Opportunities in Assessing and Regulating Organohalogen Flame Retardants (OFRs) as a Class in Consumer Products.Environmental health perspectives · 2024Article
- Hormonal Injustice: Environmental Toxicants as Drivers of Endocrine Health Disparities.Endocrinology and metabolism clinics of North America · 2023Review
- Proteomic analyses of primary human villous trophoblasts exposed to flame retardant BDE-47 using SWATH-MS.Toxicology · 2023Article
- Racial and ethnic disparities in preterm birth: a mediation analysis incorporating mixtures of polybrominated diphenyl ethers.Frontiers in reproductive health · 2023Article
- Polybrominated diphenyl ethers in early pregnancy and preterm birth: Findings from the NICHD Fetal Growth Studies.International journal of hygiene and environmental health · 2022Article
- Gene expression profiling after exposure to a chemical carcinogen, Pentabrominated Diphenyl Ether, at different life stages.Frontiers in toxicology · 2022Article
- Associations Between Polybrominated Diphenyl Ethers Concentrations in Human Placenta and Small for Gestational Age in Southwest China.Frontiers in public health · 2022Article
- Associations between prenatal maternal exposure to per- and polyfluoroalkyl substances (PFAS) and polybrominated diphenyl ethers (PBDEs) and birth outcomes among pregnant women in San Francisco.Environmental health : a global access science source · 2020Article
- Association of polybrominated diphenyl ether (PBDE) levels with biomarkers of placental development and disease during mid-gestation.Environmental health : a global access science source · 2020Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
Prenatal polybrominated diphenyl ether (PBDE) exposures are a public health concern due to their persistence and potential for reproductive and developmental harm. However, we have little information about the extent of fetal exposures during critical developmental periods and the variation in exposures for groups that may be more highly exposed, such as communities of color and lower socioeconomic status (SES). To characterize maternal-fetal PBDE exposures among potentially vulnerable groups, PBDE levels were examined in the largest sample of matched maternal serum, placenta, and fetal liver tissues during mid-gestation among a geographically, racially/ethnically, and socially diverse population of pregnant women from Northern California and the Central Valley (n = 180; 2014-16). Maternal-fetal PBDE levels were compared to population characteristics using censored Kendall's tau correlation and linear regression. PBDEs were commonly detected in all biomatrices. Before lipid adjustment, wet-weight levels of all four PBDE congeners were highest in the fetal liver (p < 0.001), whereas median PBDE levels were significantly higher in maternal serum than in the fetal liver or placenta after lipid-adjustment (p < 0.001). We also found evidence of racial/ethnic disparities in PBDE exposures (Non-Hispanic Black > Latina/Hispanic > Non-Hispanic White > Asian/Pacific Islander/Other; p < 0.01), with higher levels of BDE-100 and BDE-153 among non-Hispanic Black women compared to the referent group (Latina/Hispanic women). In addition, participants living in Fresno/South Central Valley had 34% (95% CI: - 2.4 to 84%, p = 0.07) higher wet-weight levels of BDE-47 than residents living in the San Francisco Bay Area. PBDEs are widely detected and differentially distributed in maternal-fetal compartments. Non-Hispanic Black pregnant women and women from Southern Central Valley geographical populations may be more highly exposed to PBDEs. Further research is needed to identify sources that may be contributing to differential exposures and associated health risks among these vulnerable populations.
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