ArticleScientific reports2020
Identification of sequence polymorphisms at 58 STRs and 94 iiSNPs in a Tibetan population using massively parallel sequencing.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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17 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Systematic analysis of population studies performed with the ForenSeq™ DNA Signature Prep kit.Journal of forensic sciences · 2025Pooled it
- Swedish population data for 37 autosomal, 12 X-chromosomal and 23 Y-chromosomal STR loci.International journal of legal medicine · 2026Article
- Revisiting guidance on population sampling for highly polymorphic STR loci.Forensic science international. Genetics · 2026Article
- Forensic utilization of NGS-STRs and evaluation of system efficacy for different kinship identifications.Human genomics · 2025Article
- Review
- Parallel sequencing of 170 STR and 132 SNP markers using the FGID forensic four-in-one DNA typing kit on the DNBSEQ-G99RS platform.Forensic sciences research · 2025Article
- Past, Present and Future Perspectives of Forensic Genetics.Biomolecules · 2025Review
- Population genetic analyses of Eastern Chinese Han nationality using ForenSeq™ DNA Signature Prep Kit.Molecular genetics and genomics : MGG · 2024Article
- Recent advances in forensic biology and forensic DNA typing: INTERPOL review 2019-2022.Forensic science international. Synergy · 2023Article
- Characterization of 58 STRs and 94 SNPs with the ForenSeq™ DNA signature prep kit in Mexican-Mestizos from the Monterrey city (Northeast, Mexico).Molecular biology reports · 2022Article
- The transitivity of the Hardy-Weinberg law.Forensic science international. Genetics · 2022Article
- Development and validation of a novel 133-plex forensic STR panel (52 STRs and 81 Y-STRs) using single-end 400 bp massive parallel sequencing.International journal of legal medicine · 2022Article
- Applications of massively parallel sequencing in forensic genetics.Genetics and molecular biology · 2022Article
- Sequence variations, flanking region mutations, and allele frequency at 31 autosomal STRs in the central Indian population by next generation sequencing (NGS).Scientific reports · 2021Article
- Concordance and characterization of massively parallel sequencing at 58 STRs in a Tibetan population.Molecular genetics & genomic medicine · 2021Article
- Article
- Densitometry of STR-PAGE for donor chimerism in acute leukemia's: A simple method for routine use.Pakistan journal of medical sciencesArticle
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Massively parallel sequencing (MPS) has rapidly become a promising method for forensic DNA typing, due to its ability to detect a large number of markers and samples simultaneously in a single reaction, and sequence information can be obtained directly. In the present study, two kinds of forensic genetic markers, short tandem repeat (STR) and identity-informative single nucleotide polymorphism (iiSNP) were analyzed simultaneously using ForenSeq DNA Signature Prep Kit, a commercially available kit on MPS platform. A total of 152 DNA markers, including 27 autosomal STR (A-STR) loci, 24 Y chromosomal STR (Y-STR) loci, 7 X chromosomal STR (X-STR) loci and 94 iiSNP loci were genotyped for 107 Tibetan individuals (53 males and 54 females). Compared with length-based STR typing methods, 112 more A-STR alleles, 41 more Y-STR alleles, and 24 more X-STR alleles were observed at 17 A-STRs, 9 Y-STRs, and 5 X-STRs using sequence-based approaches. Thirty-nine novel sequence variations were observed at 20 STR loci. When the flanking regions were also analyzed in addition to target SNPs at the 94 iiSNPs, 38 more alleles were identified. Our study provided an adequate genotype and frequencies data of the two types of genetic markers for forensic practice. Moreover, we also proved that this panel is highly polymorphic and informative in Tibetan population, and should be efficient in forensic kinship testing and personal identification cases.
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