Evidence map›Paper›PMID 32699206›Full record

ArticleCell death & disease2020

WWP1 germline variants are associated with normocephalic autism spectrum disorder.

Giuseppe Novelli, Antonio Novelli, Paola Borgiani, Dario Cocciadiferro, Michela Biancolella, Emanuele Agolini, Marco Pietrosanto, Rosario Casalone, Manuela Helmer-Citterich, Emiliano Giardina and 4 more

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell death & disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Lack of evidence for germlineGenes & diseases · 2024
    Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Giuseppe NovelliDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, 00133, Rome, Italy. novelli@med.uniroma2.it.ORCID http://orcid.org/0000-0002-7781-602X
Antonio NovelliLaboratory of Medical Genetics, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Paola BorgianiDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, 00133, Rome, Italy.
Dario CocciadiferroLaboratory of Medical Genetics, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Michela BiancolellaDepartment of Biology, Tor Vergata University of Rome, 00133, Rome, Italy.
Emanuele AgoliniLaboratory of Medical Genetics, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Marco PietrosantoDepartment of Biology, Tor Vergata University of Rome, 00133, Rome, Italy.
Rosario CasaloneCytogenetics and Medical Genetics Laboratory, Ospedale di Circolo, ASST Sette Laghi, Varese, Italy.
Manuela Helmer-CitterichDepartment of Biology, Tor Vergata University of Rome, 00133, Rome, Italy.
Emiliano GiardinaDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, 00133, Rome, Italy.
Suresh K JainIntonation Research Laboratories Pvt. Ltd, Hyderabad, Telangana, 500076, India.
Wenyi WeiCancer Research Institute, Beth Israel Deaconess Cancer Center, Harvard Medical School, Boston, MA, 02215, USA.ORCID http://orcid.org/0000-0003-0512-3811
Charis EngGenomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.ORCID http://orcid.org/0000-0002-3693-5145
Pier Paolo PandolfiMBC, Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, TO, 10126, Italy. pierpaolo.pandolfiderinaldis@unito.it.

Funding

Targeting Tumor Suppressive Pathways for Cancer TherapyR35CA197529 · NCI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI PANDOLFI, PIER PAOLO · 2015 to 2019
$4.6M
NCI NIH HHS R35 CA197529
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Autism Spectrum DisorderCraniosynostosesNeoplasmsGain of Function MutationGerm CellsHumansPTEN PhosphohydrolaseUbiquitin-Protein LigasesPTEN PhosphohydrolasePTEN protein, humanUbiquitin-Protein LigasesWWP1 protein, human

Identifiers

PMID32699206
PMCPMC7376150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.